Temple W J, Bramwell V, Eisenhauer E, Jenkin R D, Langer F, Worth A J
Canadian Sarcoma Group (CSG), National Cancer Institute of Canada.
Can J Surg. 1988 Nov;31(6):410-2.
The Canadian Sarcoma Group was formed in 1985 by interested surgeons, oncologists and pathologists. In the evaluation of new protocols, standard surgical guidelines have been developed which incorporate the concepts of multimodality therapy, particularly radiotherapy and chemotherapy. Also defined are the procedures performed: biopsy, marginal resection, wide local excision, radical resection and the principles to be considered when doing a diagnostic biopsy and a curative resection, particularly with limb salvage in mind. To optimize local control of the disease, centres treating sarcomas should have access to computed tomography, radionuclide scanning, to radiation and medical oncologists, and members of other surgical specialties. This team approach increases survival by 10% and also provides the best circumstances in which to study adjuvant therapy. Surgical guidelines are also essential in order to compare the results of different clinical trials.
加拿大肉瘤研究小组于1985年由感兴趣的外科医生、肿瘤学家和病理学家组成。在评估新方案时，已制定了标准手术指南，其中纳入了多模式治疗的概念，特别是放疗和化疗。还明确了所实施的手术程序：活检、边缘切除、广泛局部切除、根治性切除，以及在进行诊断性活检和根治性切除时应考虑的原则，尤其要考虑肢体保全。为了优化对该疾病的局部控制，治疗肉瘤的中心应具备计算机断层扫描、放射性核素扫描设备，有放射肿瘤学家和医学肿瘤学家以及其他外科专业的成员。这种团队协作方法可使生存率提高10%，也为研究辅助治疗提供了最佳条件。手术指南对于比较不同临床试验的结果也至关重要。
