Zheng Jie, Yang Qiu-Jin, Dang Fu-Tao, Yang Jing
Department of Gastroenterology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China.
Department of Gastroenterology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China.
Arab J Gastroenterol. 2019 Dec;20(4):183-188. doi: 10.1016/j.ajg.2019.11.005. Epub 2019 Dec 2.
Drug-induced pancreatitis is a disease that is receiving increasing attention. This article reviews the advances in the incidence, risk factors, pathogenesis, diagnosis, treatment and prevention of drug-induced pancreatitis by reviewing the literature on drug-induced pancreatitis, especially in the literature of the latest 10 years. The incidence of drug-induced pancreatitis is relatively low, however, there is an increasing trend with the widespread use of drugs, and the incidence seems to be related to regional distribution. There is currently lack of data on the epidemiology of drug-induced pancreatitis in China. In recent years, research on the pathogenesis of drug-induced pancreatitis has made some progress, but further research is needed. Drug-induced pancreatitis is a diagnosis of exclusion. With further understanding and research, a new diagnostic approach has been proposed. Pharmacogenomics is expected to help prevent and perform an individual treatment of drug-induced pancreatitis.
药物性胰腺炎是一种日益受到关注的疾病。本文通过回顾药物性胰腺炎的相关文献,特别是近10年的文献,综述了药物性胰腺炎在发病率、危险因素、发病机制、诊断、治疗及预防等方面的研究进展。药物性胰腺炎的发病率相对较低,然而,随着药物的广泛使用,其发病率呈上升趋势,且发病率似乎与地区分布有关。目前中国缺乏药物性胰腺炎的流行病学数据。近年来,药物性胰腺炎发病机制的研究取得了一些进展,但仍需进一步研究。药物性胰腺炎是一种排除性诊断。随着进一步的认识和研究,已提出了新的诊断方法。药物基因组学有望有助于预防和实施药物性胰腺炎的个体化治疗。