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延迟发作的洛沙坦引起的胰腺炎继发于过量:一例报告。

Delayed-Onset Losartan-Induced Pancreatitis Secondary to an Overdose: A Case Report.

机构信息

CUNY School of Medicine, New York, USA.

St. Barnabas Hospital, Bronx, NY, USA.

出版信息

J Investig Med High Impact Case Rep. 2023 Jan-Dec;11:23247096231165737. doi: 10.1177/23247096231165737.

Abstract

Acute pancreatitis is defined as inflammation of the pancreas and is most commonly caused by gallstones and alcohol use. Less commonly, acute pancreatitis can be drug induced from medications that are divided into 5 subgroups (classes Ia-V). The subgroups are determined based on the cases reported, reaction with rechallenge and a consistent period of latency. We describe a case of a 34-year-old female who overdosed on losartan pills in a suicide attempt but developed symptoms of drug-induced acute pancreatitis nearly a week later without gallstones, alcohol involvement, or other drug toxicity.

摘要

急性胰腺炎是胰腺的炎症,最常见的病因是胆石症和饮酒。不常见的病因是药物引起的,这些药物可分为 5 个亚组(Ia-V 类)。这些亚组是根据报告的病例、与再激发试验的反应和一致的潜伏期来确定的。我们描述了一位 34 岁女性的病例,她试图自杀时过量服用了洛沙坦片,但在近一周后出现了药物引起的急性胰腺炎症状,没有胆石症、酒精摄入或其他药物毒性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d36/10102932/2806fd52d652/10.1177_23247096231165737-fig1.jpg

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