弹性蛋白的进化研究——I. 系统发育分布

Studies on the evolution of elastin--I. Phylogenetic distribution.

Sage H, Gray W R

Department of Biology, University of Utah, Salt Lake City 84112.

Comp Biochem Physiol B. 1979;64(4):313-27. doi: 10.1016/0305-0491(79)90277-3.

Abstract

Aortae and other tissues from numerous animals were examined for the presence of the rubbery protein elastin by (a) chemical purification and amino acid analysis, (b) presence of the cross-linking amino acids desmosine and isodesmosine and (c) histological staining. 2. Elastin was found in all vertebrates examined (42 species) with the exception of cyclostomes (3 species). It was absent from all invertebrates tested (14 species). 3. The amino acid compositions of vertebrate elastins showed marked and interesting interspecies variations.

摘要

通过以下方法检查了来自众多动物的主动脉及其他组织中是否存在橡胶状蛋白质弹性蛋白：(a) 化学纯化和氨基酸分析；(b) 交联氨基酸锁链素和异锁链素的存在情况；(c) 组织学染色。2. 在所检查的所有脊椎动物（42种）中都发现了弹性蛋白，但圆口纲动物（3种）除外。在所有测试的无脊椎动物（14种）中均未发现弹性蛋白。3. 脊椎动物弹性蛋白的氨基酸组成显示出显著且有趣的种间差异。