Bolanos Jose, Morgentaler Abraham
Men's Health Boston, Chestnut Hill, MA, USA.
Men's Health Boston, Beth Israel Deaconess Medical Center, Harvard Medical School, Chestnut Hill, MA, USA.
Urol Case Rep. 2019 Nov 22;29:101078. doi: 10.1016/j.eucr.2019.101078. eCollection 2020 Mar.
Post-orgasmic illness syndrome (POIS) is an uncommon condition in which men experience debilitating symptoms following orgasm, including anxiety, weakness, and lassitude. The etiology is unknown, and treatment challenging. We present a 25y man with POIS since puberty. He dreaded ejaculation due to his subsequent symptoms. Multiple prior treatments had failed. Blood tests revealed testosterone (T) deficiency. hCG was prescribed. At 6 weeks T levels normalized with near-complete resolution of symptoms. This successful result argues for hormonal investigation in men with POIS, and a trial of hCG or T therapy if total or free T is low or borderline.
性高潮后疾病综合征(POIS)是一种罕见的病症,男性在性高潮后会出现使人衰弱的症状,包括焦虑、虚弱和疲倦。其病因不明,治疗具有挑战性。我们报告一名自青春期起就患有POIS的25岁男性。由于随后出现的症状,他害怕射精。之前的多种治疗均失败。血液检查显示睾酮(T)缺乏。于是给他开了人绒毛膜促性腺激素(hCG)。6周时,T水平恢复正常,症状几乎完全缓解。这一成功结果表明,对于患有POIS的男性应进行激素检查,如果总T或游离T水平低或处于临界值,应尝试hCG或T治疗。