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性高潮后疾病综合征:历史与现状。

Post-orgasmic illness syndrome: history and current perspectives.

机构信息

The Men's Health Center, Miriam Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island; Division of Urology, Warren Alpert Medical School of Brown University, Providence, Rhode Island.

Division of Urology, Warren Alpert Medical School of Brown University, Providence, Rhode Island.

出版信息

Fertil Steril. 2020 Jan;113(1):13-15. doi: 10.1016/j.fertnstert.2019.11.021.

DOI:10.1016/j.fertnstert.2019.11.021
PMID:32033716
Abstract

Post-orgasmic illness syndrome is a rare disorder causing a debilitating cluster of flu-like and allergic type symptoms that occur within seconds, minutes or hours after ejaculation. Symptoms occur after intercourse, masturbation or spontaneous ejaculation and last from 2 to 7 days. The condition is chronic and follows a primary pattern occurring in adolescence and a secondary acquired pattern with onset later in life. The true incidence is unknown as the condition is likely under-reported and under-diagnosed. The pattern of symptoms suggests an allergic or auto-immune etiology; however, the exact pathophysiology is unknown and there is no effective treatment. Men suffering from post-orgasmic illness syndrome describe emotional trauma and significant impairment of their quality of life.

摘要

性高潮后疾病综合征是一种罕见的疾病,会导致一系列类似于流感和过敏的衰弱症状,这些症状在射精后几秒钟、几分钟或几小时内出现。症状发生在性交、自慰或自发性射精后,持续 2 到 7 天。这种情况是慢性的,遵循青春期发生的原发性模式和以后生活中发生的继发性获得性模式。由于这种情况可能报告不足和诊断不足,因此真正的发病率尚不清楚。症状模式表明存在过敏或自身免疫病因;然而,确切的病理生理学尚不清楚,也没有有效的治疗方法。患有性高潮后疾病综合征的男性会感到情绪创伤,并对其生活质量造成重大影响。

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Post-orgasmic illness syndrome: history and current perspectives.性高潮后疾病综合征:历史与现状。
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Post-Orgasmic Illness Syndrome: A Review.性高潮后疾病综合征:综述。
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Clinical experience with post-orgasmic illness syndrome (POIS) patients-characteristics and possible treatment modality.与性高潮后疾病综合征 (POIS) 患者相关的临床经验——特征和可能的治疗方式。
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引用本文的文献

1
Post-orgasmic illness syndrome and its effects on self esteem and relationships: a survey.性高潮后疾病综合征及其对自尊和人际关系的影响:一项调查
Int J Impot Res. 2025 Jun 16. doi: 10.1038/s41443-025-01103-9.
2
Post orgasmic illness syndrome: a review.性高潮后疾病综合征:综述
Int J Impot Res. 2024 Mar 14. doi: 10.1038/s41443-024-00860-3.
3
Case series: expanding diagnostic markers in postorgasmic illness syndrome.病例系列:后性高潮疾病综合征中不断扩展的诊断标志物
Sex Med. 2023 Mar 2;11(2):qfac021. doi: 10.1093/sexmed/qfac021. eCollection 2023 Apr.
4
Novel treatment for post-orgasmic illness syndrome: a case report and literature review.性高潮后疾病综合征的新型治疗方法:一例病例报告及文献综述
Asian J Androl. 2022 May-Jun;24(3):332-334. doi: 10.4103/aja202170.