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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Van Balgooy J N, Roberts E

Division of Neurosciences, City of Hope National Medical Center, Duarte, CA 91010.

Comp Biochem Physiol B. 1979;62(3):263-8. doi: 10.1016/0305-0491(79)90211-6.

Superoxide dismutase (superoxide: superoxide oxido-reductase, E.C. 1.15.1.1) in different species was determined quantitatively and qualitatively. Although quantitative differences were minor, there were significant differences in the isoenzyme patterns among the species. 2. No quantitative differences were found in superoxide dismutase (SOD) activities in the brains of mice between 1 and 23 days of age. The mitochondrial isoenzyme increased with age, attaining maximal levels between 9 and 12 days. In the six, regions of adult rat brain studied, highest values of SOD were found in the hypothalamus and lowest in the cortex. 3. SOD levels generally were lower in several transplantable mouse and rat tumors than in normal tissues of these species. Mn-SOD was not detected in the tumors studied by the methods employed.

对不同物种中的超氧化物歧化酶（超氧化物：超氧化物氧化还原酶，E.C. 1.15.1.1）进行了定量和定性测定。尽管定量差异较小，但各物种间的同工酶模式存在显著差异。2. 在1至23日龄小鼠的大脑中，未发现超氧化物歧化酶（SOD）活性存在定量差异。线粒体同工酶随年龄增加，在9至12日龄时达到最高水平。在所研究的成年大鼠大脑的六个区域中，下丘脑的SOD值最高，而皮质中的最低。3. 几种可移植的小鼠和大鼠肿瘤中的SOD水平通常低于这些物种的正常组织。在所研究的肿瘤中，采用所使用的方法未检测到锰超氧化物歧化酶（Mn-SOD）。

Van Balgooy J N, Roberts E

Division of Neurosciences, City of Hope National Medical Center, Duarte, CA 91010.

Comp Biochem Physiol B. 1979;62(3):263-8. doi: 10.1016/0305-0491(79)90211-6.

Superoxide dismutase (superoxide: superoxide oxido-reductase, E.C. 1.15.1.1) in different species was determined quantitatively and qualitatively. Although quantitative differences were minor, there were significant differences in the isoenzyme patterns among the species. 2. No quantitative differences were found in superoxide dismutase (SOD) activities in the brains of mice between 1 and 23 days of age. The mitochondrial isoenzyme increased with age, attaining maximal levels between 9 and 12 days. In the six, regions of adult rat brain studied, highest values of SOD were found in the hypothalamus and lowest in the cortex. 3. SOD levels generally were lower in several transplantable mouse and rat tumors than in normal tissues of these species. Mn-SOD was not detected in the tumors studied by the methods employed.

对不同物种中的超氧化物歧化酶（超氧化物：超氧化物氧化还原酶，E.C. 1.15.1.1）进行了定量和定性测定。尽管定量差异较小，但各物种间的同工酶模式存在显著差异。2. 在1至23日龄小鼠的大脑中，未发现超氧化物歧化酶（SOD）活性存在定量差异。线粒体同工酶随年龄增加，在9至12日龄时达到最高水平。在所研究的成年大鼠大脑的六个区域中，下丘脑的SOD值最高，而皮质中的最低。3. 几种可移植的小鼠和大鼠肿瘤中的SOD水平通常低于这些物种的正常组织。在所研究的肿瘤中，采用所使用的方法未检测到锰超氧化物歧化酶（Mn-SOD）。