在大肠杆菌中进化出新乳糖酶功能所需的突变数量。
Number of mutations required to evolve a new lactase function in Escherichia coli.
作者信息
Hall B G
出版信息
J Bacteriol. 1977 Jan;129(1):540-3. doi: 10.1128/jb.129.1.540-543.1977.
Abstract
The frequency of mutation of the ebgAo allele to ebgA+ was compared with the frequency of mutation of strA+ to strA-. The observation that both spontaneous and ethyl methane sulfonate-induced mutations to ebgA+ occurred more frequently than mutations to strA- suggests that ebgA+ mutants arise as the result of single-point mutations.
摘要
将ebgAo等位基因突变为ebgA+的频率与strA+突变为strA-的频率进行了比较。自发突变和甲磺酸乙酯诱导的突变为ebgA+的频率均高于突变为strA-的频率，这一观察结果表明ebgA+突变体是单点突变的结果。
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