Abou Zahr Rawad, Chalhoub Khalil, Matta Imad, Horani Sawsan, Bedoyan Zarouhie, El Hachem Georges, Ghantous Imad, Jabbour Michel
Department of Urology, University of Balamand, Saint George Hospital University Medical Center, Beirut 1100 2807, Lebanon.
University of Balamand, Faculty of Medicine and Medical Sciences, Beirut 1100 2807, Lebanon.
Case Rep Urol. 2019 Nov 24;2019:4391015. doi: 10.1155/2019/4391015. eCollection 2019.
Testicular cancer is the most frequent solid tumor detected in young adult men. Germ cell tumors (GCTs), particularly seminomas, are the most common type of testicular neoplasms seen in that age population. Most publications have reported decreasing incidence of GCTs in patients above forty years of age. Since the biologic activity of seminomas appears similar across ages, recommended management of senior adults involves a multimodal therapy of radical inguinal orchiectomy with radiation or cytotoxic treatment as needed. Attenuating chemotherapy dosages are critical to ensure better tolerability of associated adverse events. Here we report a case series of 2 men older than fifty years of age with metastatic testicular seminoma. We aim to emphasize a rare clinical entity encountered in the senior adult population.
睾丸癌是年轻成年男性中最常见的实体瘤。生殖细胞肿瘤（GCTs），尤其是精原细胞瘤，是该年龄人群中最常见的睾丸肿瘤类型。大多数出版物报道，40岁以上患者的GCTs发病率呈下降趋势。由于精原细胞瘤的生物学活性在各年龄段似乎相似，因此建议对老年患者采用多模式治疗，即根据需要进行根治性腹股沟睾丸切除术，并联合放疗或细胞毒性治疗。降低化疗剂量对于确保更好地耐受相关不良事件至关重要。在此，我们报告了2例年龄超过50岁的转移性睾丸精原细胞瘤病例系列。我们旨在强调在老年人群中遇到的一种罕见临床情况。
