Das Gupta Rajat, Haider Shams Shabab, Hashan Mohammad Rashidul, Rahman Muhammad Aziz, Sarker Malabika
Centre of Excellence for Non-Communicable Diseases and Nutrition, BRAC James P Grant School of Public Health BRAC University Dhaka Bangladesh.
Centre of Excellence for Science of Implementation and Scale-Up, BRAC James P Grant School of Public Health BRAC University Dhaka Bangladesh.
Health Sci Rep. 2019 Nov 7;2(12):e141. doi: 10.1002/hsr2.141. eCollection 2019 Dec.
The burden of hypertension is increasing in Nepal. Different studies have evaluated the relationship between height and blood pressure in different regions, with mixed results. The relationship between height and hypertension has not yet been explored in the Nepalese context. Given this knowledge gap, this study aims to determine the relationship between height and hypertension among Nepalese adults (aged ≥18 years).
This study utilized the dataset from the Nepal Demographic and Health Survey (NDHS) 2016. Hypertension was defined as systolic blood pressure ≥ 140 mmHg and/or a diastolic blood pressure ≥ 90 mmHg. Height, measured in centimeters (cm), was analyzed as a continuous variable. Based on previous evidence, the following covariates were considered: age, sex, presence of overweight or obesity, educational status, household wealth status, and place, province, and ecological zone of residence. Multilevel multivariable logistic regression was done to evaluate the association between height and hypertension. Both crude odds ratio (COR) and adjusted odds ratio (AOR) are reported, along with a 95% confidence interval (CI). Sample weight of NDHS was adjusted during analysis.
Among 13 393 weighted individuals over the age of 18 years, the prevalence of hypertension in Nepal was found to be 21.1% (95% CI, 19.9%-22.4%). In the final multivariable model, after adjusting for relevant covariates, it was found that height was inversely associated with hypertension. For a Nepalese adult, the odds of hypertension decreased by 10% with each 10-cm increase in height (AOR 0.9; 95% CI 0.8-0.9; = 0.003).
Awareness should be raised among people with low stature for prevention of hypertension. Longitudinal studies are recommended to include genetic and social/environmental determinants of stature in the analyses.
尼泊尔高血压负担日益加重。不同研究评估了不同地区身高与血压之间的关系，结果不一。尼泊尔国内尚未探讨身高与高血压之间的关系。鉴于这一知识空白，本研究旨在确定尼泊尔成年人（年龄≥18岁）身高与高血压之间的关系。
本研究使用了2016年尼泊尔人口与健康调查（NDHS）的数据集。高血压定义为收缩压≥140 mmHg和/或舒张压≥90 mmHg。以厘米（cm）为单位测量的身高作为连续变量进行分析。基于先前的证据，考虑了以下协变量：年龄、性别、超重或肥胖情况、教育程度、家庭财富状况以及居住的地点、省份和生态区。采用多水平多变量逻辑回归来评估身高与高血压之间的关联。报告了粗比值比（COR）和调整后的比值比（AOR）以及95%置信区间（CI）。分析过程中对NDHS的样本权重进行了调整。
在13393名年龄超过18岁的加权个体中，尼泊尔高血压患病率为21.1%（95% CI，19.9%-22.4%）。在最终的多变量模型中，在调整相关协变量后，发现身高与高血压呈负相关。对于尼泊尔成年人，身高每增加10厘米，患高血压的几率降低10%（AOR 0.9；95% CI 0.8-0.9；P = 0.003）。
应提高身材矮小者对预防高血压的认识。建议开展纵向研究，在分析中纳入身高的遗传和社会/环境决定因素。
