Tsugane S, Watanabe S, Sugimura H, Otsu T, Tobinai K, Shimoyama M, Nanri S, Ishii H
Epidemiology Division, National Cancer Center Research Institute, Tokyo, Japan.
Am J Epidemiol. 1988 Nov;128(5):1153-61. doi: 10.1093/oxfordjournals.aje.a115058.
Serologic tests for human T lymphotropic virus type I (HTLV-I) and hepatitis B virus infections were conducted in 1986 in two Japanese immigrant colonies located in Santa Cruz, Bolivia. A total of 322 adults (283 Japanese and 39 Bolivians) over age 35 years and 305 children (166 Japanese, 124 Bolivians, and 15 of mixed blood) aged 8-17 years were sampled at the time of a routine health checkup. The prevalence of antibody to HTLV-I was 17% in first-generation Japanese immigrants and 6% in second- or third-generation Japanese children. Prevalences among native Bolivians were 3% and 5% in adults and children, respectively. Seropositive Japanese immigrants and mothers showed clustering according to birthplace in endemic areas of Japan. The prevalence of either hepatitis B virus surface antigen (HBsAg) or antibody to HBsAg was 48% in Japanese adults, 21% in Japanese children, 13% in Bolivian adults, and 1% in Bolivian children. Seropositive adults did not show clustering according to birthplace, but children in one colony showed clustering and a narrow age range. A correlation of seropositivity between husbands and wives was found only for HTLV-I. The seropositivity was independent of whether an HTLV-I or a hepatitis B virus infection marker was present.
1986年，在玻利维亚圣克鲁斯的两个日本移民聚居地，对人类嗜T淋巴细胞病毒I型（HTLV-I）和乙肝病毒感染进行了血清学检测。在一次常规健康检查时，共采集了322名35岁以上的成年人（283名日本人，39名玻利维亚人）以及305名8至17岁的儿童（166名日本人，124名玻利维亚人，15名混血儿）的样本。第一代日本移民中HTLV-I抗体的流行率为17%，第二代或第三代日本儿童中为6%。玻利维亚本地人中，成年人和儿童的流行率分别为3%和5%。血清反应阳性的日本移民和母亲根据其在日本流行地区的出生地呈现聚集现象。乙肝病毒表面抗原（HBsAg）或HBsAg抗体的流行率在日本成年人中为48%，在日本儿童中为21%，在玻利维亚成年人中为13%，在玻利维亚儿童中为1%。血清反应阳性的成年人未根据出生地呈现聚集现象，但一个聚居地的儿童呈现聚集且年龄范围较窄。仅在HTLV-I方面发现夫妻之间血清反应阳性存在相关性。血清反应阳性与是否存在HTLV-I或乙肝病毒感染标志物无关。
