Baba S, Yamaguchi J, Horie M
Laboratory of Physical and Pharmaceutical Chemistry, Tokyo College of Pharmacy, Japan.
Anal Biochem. 1988 Aug 15;173(1):190-5. doi: 10.1016/0003-2697(88)90177-7.
Measurement of specific radioactivity by a high-performance liquid chromatograph with a synchronized accumulating radioisotope detector was conducted. Accuracy of measurement for an authentic sample containing 0.2 nCi of tryptophan labeled with carbon-14 exceeded 95%. In the case of a plasma sample obtained 120 min following intravenous administration of 15 muCi of labeled tryptophan to a rat, the coefficient of variation was 7.0%.
采用配备同步累积放射性同位素检测器的高效液相色谱仪进行了比放射性的测量。对含有0.2纳居里碳-14标记色氨酸的标准样品的测量准确度超过95%。在给大鼠静脉注射15微居里标记色氨酸120分钟后采集的血浆样品中，变异系数为7.0%。
