在高心率时 CT 与 SPECT 射血分数计算的比较：动态心脏体模研究。
Comparison of ejection fraction calculation between CT and SPECT at high heart rate: A dynamic cardiac phantom study.
机构信息
Department of Cardiology, Show Chwan Memorial Hospital, Changhua, Taiwan.
Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
出版信息
J Nucl Cardiol. 2021 Feb;28(1):311-316. doi: 10.1007/s12350-019-01991-7. Epub 2020 Jan 6.
The purpose of this study is to compare the ejection fraction (EF) calculation of CT and SPECT at high heart rate. A dynamic cardiac phantom with programmable end-systolic volume (ESV), end-diastolic volume (EDV), and heart rate was used to compare CT, which has high spatial resolution (< 1 mm) and modest temporal resolution of 175 msec, and SPECT, which has high temporal resolution of 16 bins per cardiac cycle but poor spatial resolution (> 1 cm) in EF, ESV, and EDV at the heart rates ≤ 100 bpm for EF = 30 (disease state) and EF = 60 (healthy state). EF calculations for SPECT were accurate in 2% for 40 to 100 bpm for both EF = 30 and EF = 60, and were not heart rate dependent although both ESV and EDV could be underestimated by 18-20%. EF calculations for CT were accurate in 2.2% for 40 and 60 bpm. Inaccuracy in EF calculations, ESV and EDV estimates increased when the heart rate or EF increased. SPECT was accurate for EF calculation for the heart rates ≤ 100 bpm and CT was accurate for the heart rates of ≤ 60 bpm. CT was less accurate for the high heart rates of 80 and 100 bpm, or high EF = 60.
本研究旨在比较高心率下 CT 和 SPECT 的射血分数（EF）计算。使用具有可编程收缩末期容积（ESV）、舒张末期容积（EDV）和心率的动态心脏体模，比较 CT（空间分辨率高（<1mm），时间分辨率适中（175 毫秒））和 SPECT（时间分辨率高（每心脏周期 16 个-bin），但 EF、ESV 和 EDV 的空间分辨率差（>1cm））在 EF=30（疾病状态）和 EF=60（健康状态）的心率≤100 bpm 时的 EF、ESV 和 EDV。SPECT 的 EF 计算在 40 到 100 bpm 时对于 EF=30 和 EF=60 的准确性均为 2%，并且不受心率影响，尽管 ESV 和 EDV 可能会低估 18-20%。CT 的 EF 计算在 40 和 60 bpm 时的准确性为 2.2%。随着心率或 EF 的增加，EF、ESV 和 EDV 估计的准确性降低。SPECT 在心率≤100 bpm 时 EF 计算准确，CT 在心率≤60 bpm 时准确。CT 在 80 和 100 bpm 或高 EF=60 的高心率时准确性较差。
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