角膜塑形镜治疗近视后眼轴长度的变化：一项荟萃分析。
Changes in axial length after orthokeratology lens treatment for myopia: a meta-analysis.
作者信息
Guan Meng, Zhao Weijia, Geng Yu, Zhang Yang, Ma Jia, Chen Zonghan, Peng Mingqian, Li Yan
机构信息
Department of Ophthalmology, First Affiliated Hospital of Kunming Medical University, 295 Xichang Road, Kunming, 650031, Yunnan Province, China.
Department of Dermatology, First Affiliated Hospital of Kunming Medical University, Kunming, 650031, Yunnan Province, China.
出版信息
Int Ophthalmol. 2020 Jan;40(1):255-265. doi: 10.1007/s10792-019-01167-9. Epub 2020 Jan 8.
PURPOSE
Orthokeratology (OK) lens is a popular optical method to control myopia progression. This study aimed to assess the effect of OK lens on axial length change compared with glasses.
METHODS
PubMed, Web of Science, and Embase were searched to retrieve the related articles. Then, the articles were selected according to predefined criteria. Standardized mean difference (SMD) and 95% confidence interval (CI) were selected as effect size for combining and analyzing the change in axial length.
RESULTS
A total of 13 articles were included in the present study. Different models were selected according to the heterogeneity of each analysis. The axial length change in OKs group was significantly smaller than control group; SMD (95% CI) of change in axial length was - 0.857 (- 1.146, - 0.568), p < 0.001 at the end of 1 year and - 0.701 (- 1.675, 0.272), p < 0.001 at the end of 2 years or longer time.
CONCLUSIONS
OK lens treatment appears more effective in slowing axial elongation than glasses during the early treatment of myopia in children.
目的
角膜塑形术（OK）镜片是一种控制近视进展的常用光学方法。本研究旨在评估与眼镜相比，OK镜片对眼轴长度变化的影响。
方法
检索PubMed、科学网和Embase以获取相关文章。然后，根据预定义标准选择文章。选择标准化均数差（SMD）和95%置信区间（CI）作为效应量，以合并和分析眼轴长度的变化。
结果
本研究共纳入13篇文章。根据各分析的异质性选择不同模型。OK镜片组的眼轴长度变化明显小于对照组；1年末眼轴长度变化的SMD（95%CI）为-0.857（-1.146，-0.568），p<0.001；2年末或更长时间时为-0.701（-1.675，0.272），p<0.001。
结论
在儿童近视的早期治疗中，OK镜片治疗在减缓眼轴伸长方面似乎比眼镜更有效。
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