Addiction Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Addiction Switzerland, Lausanne, Switzerland.
Addiction. 2020 Aug;115(8):1459-1469. doi: 10.1111/add.14967. Epub 2020 Feb 5.
To estimate age-specific changes in hospital admissions for alcohol intoxication following two consecutive restrictions on off-premises alcohol sales introduced in the canton of Vaud, Switzerland.
Primary analyses used interrupted autoregressive integrated moving average (ARIMA) time-series analyses (repeated cross-sectional), with Lausanne and Vaud as experimental sites and the rest of Switzerland as the control. Secondary analyses used, for example, a different control site (other French-speaking cantons only) or a different statistical model.
Switzerland between 2010 and 2016.
In-patients (i.e. patients assigned a bed overnight) hospitalized between 8 p.m. and 6 a.m. (n = 1 261 564), as documented in the Swiss Hospital Statistics.
Ban 1, only effective in the canton's capital, Lausanne, prohibited off-premises sales of all alcoholic beverages after 8 p.m. on Fridays and Saturdays from September 2013 to June 2015. In July 2015, Ban 2 replaced this, covered the whole canton and affected off-premises sales of beer and spirits (but not wine) after 9 p.m. (8 p.m. in Lausanne) every night of the week.
Proportions of monthly hospital admissions for alcohol intoxication (ICD-10 diagnoses F10.0/F10.1, T51.0) per 1000 monthly overall admissions.
Proportions of overall hospitalizations for alcohol intoxication declined after both bans in Lausanne [ω = -0.017, 95% confidence interval (CI) = -0.025, -0.008; ω = -0.021, 95% CI = -0.030, -0.013] but only after Ban 2 in the remainder of the canton of Vaud (ω = -0.008, 95% CI = -0.014, -0.002). Estimated changes in % were largest among 16-19-year-olds. However, as admission rates for alcohol intoxication were more frequent in adulthood than adolescence, the estimated change in number of cases was also relevant to public health among 20-69-year-olds. Secondary analyses supported the findings of the primary analyses.
Even partial restrictions of off-premises sales of alcohol in Switzerland (only 2 days per week or only for beer and spirits) appeared to reduce hospital admissions for alcohol intoxication across a wide age range (ages 16-69 years).
评估瑞士沃州连续两次限制非现场酒类销售后,因酒精中毒住院的年龄变化。
主要分析采用中断自回归综合移动平均 (ARIMA) 时间序列分析(重复横断面),以洛桑和沃州为实验点,瑞士其他地区为对照点。次要分析采用了不同的对照点(仅说法语的其他州)或不同的统计模型。
瑞士,2010 年至 2016 年。
在晚上 8 点至早上 6 点之间住院的住院患者(即分配过夜床位的患者),记录在瑞士医院统计数据中(n=1261564)。
禁令 1,仅在该州首府洛桑有效,禁止在 2013 年 9 月至 2015 年 6 月的周五和周六晚上 8 点以后出售所有含酒精饮料。2015 年 7 月,禁令 2 取代了禁令 1,覆盖整个州,影响每周每晚 9 点(洛桑为 8 点)以后的非现场啤酒和烈酒(但不包括葡萄酒)销售。
每月每 1000 例总住院人次中因酒精中毒(ICD-10 诊断 F10.0/F10.1,T51.0)的住院人数比例。
在两次禁令之后,洛桑的整体因酒精中毒住院比例下降(ω=-0.017,95%置信区间[CI]:-0.025,-0.008;ω=-0.021,95%CI:-0.030,-0.013),而沃州其余地区仅在禁令 2 之后下降(ω=-0.008,95%CI:-0.014,-0.002)。在 16-19 岁人群中,估计的变化幅度最大。然而,由于成年人因酒精中毒住院的比例高于青少年,因此 20-69 岁人群的病例数的估计变化也与公共卫生相关。次要分析支持主要分析的结果。
即使在瑞士部分限制非现场销售酒类(每周仅 2 天或仅针对啤酒和烈酒),似乎也可以降低广泛年龄组(16-69 岁)的因酒精中毒住院的人数。