Cole P, Naito K, Chaban R, Ayiomamitis A
Gage Research Institute, Toronto, Ontario, Canada.
Rhinology. 1988 Sep;26(3):209-16.
Plethysmographic rhinomanometric resistance measurements of combined and separate nasal cavities were made at a transnasal differential pressure of 100 Pa. The coefficients of variation over time of 40 consecutive total resistance values obtained at 1 min intervals from untreated noses of five healthy subjects averaged 11.0% measured directly and 11.8% calculated by application of Ohm's Law for parallel resistors. Measurements at 5 min intervals between sides increased variation of calculated total resistances markedly. The coefficients decreased to 4.7% and 5.1% respectively when the noses were decongested and by contrast with untreated noses these resistances varied independently from each other. Facial masking increased the coefficient of variation of resistance in the decongested nose (p less than 0.001) to as much as 11.0% and the magnitude of averaged resistances was moderately increased also (p less than 0.035). Measured values plotted against calculated values for total nasal resistance of 45 consecutive patients produced a regression differing insignificantly (p = 0.94) from the line of identity in the decongested nose but diverging from it (intercept 0.03 Pa/cm3/sec and slope 0.83, p less than 0.03) when the nose was untreated. Resistive variations associated with mucovascular instability and with use of a face-mask contribute substantially to differences between the results of anterior and posterior rhinomanometric assessments of total nasal resistance.
在100帕的经鼻压差下,对联合鼻腔和单独鼻腔进行体积描记法鼻阻力测量。从5名健康受试者未经治疗的鼻腔中,以1分钟的间隔连续获取40个总阻力值,其随时间的变异系数,直接测量平均为11.0%,应用并联电阻的欧姆定律计算为11.8%。两侧每隔5分钟进行测量,显著增加了计算出的总阻力的变异性。当鼻腔减充血时,变异系数分别降至4.7%和5.1%,与未经治疗的鼻腔相比,这些阻力彼此独立变化。面部面罩增加了减充血鼻腔中阻力的变异系数(p<0.001),高达11.0%,平均阻力大小也适度增加(p<0.035)。对45例连续患者的鼻腔总阻力测量值与计算值进行绘图,在减充血鼻腔中,回归与恒等线无显著差异(p = 0.94),但在鼻腔未经治疗时,与恒等线偏离(截距0.03 Pa/cm3/sec,斜率0.83,p<0.03)。与粘膜血管不稳定和使用面罩相关的阻力变化,在很大程度上导致了鼻腔总阻力前后鼻阻力评估结果之间的差异。