CIEMAT, Avd. Complutense 40, 28040 Madrid, Spain.
University of Salamanca, Campus Miguel de Unamuno, 37007 Salamanca, Spain.
Radiat Prot Dosimetry. 2020 Jul 2;188(4):477-485. doi: 10.1093/rpd/ncz307.
In case of accidental intake of radioactive material, the dose assessment requires information on the radionuclide distribution in the body. Measurements of retention or excretion are compared with model's predictions to estimate the intake. The reference models for internal dosimetry purposes are those proposed by ICRP and have been recently updated in the 'Occupational Intakes of Radionuclides (OIR)' series. This work focusses on the implementation of the new caesium model in a computer package, ICRP130Models (integrated in the toolbox BIOKMOD), together with new features aimed at estimating the intake and the dose from bioassay measurements. The software gives the best fitted intake and the committed effective dose, as well as the chi-squared test and the p-value as an indication of the goodness of the fit in the assessment process. The possibility to build the model as a function of a parameter allows the user to look for different options when fitting the bioassay measurements.
如果发生放射性物质摄入事故，剂量评估需要有关体内放射性核素分布的信息。将保留或排泄测量值与模型预测值进行比较，以估算摄入量。用于内部剂量学目的的参考模型是 ICRP 提出的模型，并在最近的“职业放射性核素摄入量（OIR）”系列中进行了更新。这项工作的重点是在计算机程序包 ICRP130Models（集成在 BIOKMOD 工具箱中）中实施新的铯模型，以及旨在估计从生物测定测量中摄入和剂量的新功能。该软件提供了最佳拟合摄入量和承诺的有效剂量，以及卡方检验和 p 值，作为评估过程中拟合度的好坏的指示。将模型构建为参数的函数的可能性允许用户在拟合生物测定测量值时寻找不同的选择。
