Coluccio Maria Laura, Pullano Salvatore A, Vismara Marco Flavio Michele, Coppedè Nicola, Perozziello Gerardo, Candeloro Patrizio, Gentile Francesco, Malara Natalia
Department of Experimental and Clinical Medicine, University of Magna Graecia, 88100 Catanzaro, Italy.
Department of Health Sciences, University of Magna Graecia, 88100 Catanzaro, Italy.
Micromachines (Basel). 2020 Jan 22;11(2):123. doi: 10.3390/mi11020123.
A long-standing goal of nanoelectronics is the development of integrated systems to be used in medicine as sensor, therapeutic, or theranostic devices. In this review, we examine the phenomena of transport and the interaction between electro-active charges and the material at the nanoscale. We then demonstrate how these mechanisms can be exploited to design and fabricate devices for applications in biomedicine and bioengineering. Specifically, we present and discuss electrochemical devices based on the interaction between ions and conductive polymers, such as organic electrochemical transistors (OFETs), electrolyte gated field-effect transistors (FETs), fin field-effect transistor (FinFETs), tunnelling field-effect transistors (TFETs), electrochemical lab-on-chips (LOCs). For these systems, we comment on their use in medicine.
纳米电子学的一个长期目标是开发集成系统,用作医学中的传感器、治疗设备或诊疗设备。在本综述中,我们研究了纳米尺度下的输运现象以及电活性电荷与材料之间的相互作用。然后,我们展示了如何利用这些机制来设计和制造用于生物医学和生物工程应用的设备。具体而言,我们介绍并讨论基于离子与导电聚合物之间相互作用的电化学设备,如有机电化学晶体管(OFET)、电解质门控场效应晶体管(FET)、鳍式场效应晶体管(FinFET)、隧穿场效应晶体管(TFET)、电化学芯片实验室(LOC)。对于这些系统,我们评论了它们在医学中的用途。