成人自动化胰岛素输注。
Automated Insulin Delivery in Adults.
机构信息
University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Box 289, Hills Road, Cambridge CB2 0QQ, UK.
University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Box 289, Hills Road, Cambridge CB2 0QQ, UK.
出版信息
Endocrinol Metab Clin North Am. 2020 Mar;49(1):167-178. doi: 10.1016/j.ecl.2019.10.007. Epub 2019 Dec 16.
Abstract
Hybrid closed-loop (artificial pancreas) systems have recently been introduced into clinical practice for adults with type 1 diabetes. This reflects successful translation from research studies in highly supervised settings to evaluation of the technology in free-living home settings. We review the different closed-loop approaches and the key clinical evidence supporting adoption of hybrid closed-loop systems for adults with type 1 diabetes. We also discuss the growing evidence for automated insulin delivery in pregnant women and in hospitalized patients with hyperglycemia. We consider the psychosocial impact of closed-loop systems and the challenges and potential future advancements for automated insulin delivery.
摘要
混合闭环（人工胰腺）系统最近已被引入临床实践，用于治疗 1 型糖尿病成人患者。这反映了从高度监管环境下的研究向在自由生活家庭环境中评估技术的成功转化。我们综述了不同的闭环方法和支持采用混合闭环系统治疗 1 型糖尿病成人患者的关键临床证据。我们还讨论了在孕妇和高血糖住院患者中自动胰岛素输送的日益增多的证据。我们考虑了闭环系统的心理社会影响以及自动胰岛素输送面临的挑战和潜在的未来进展。
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