患者X的神秘病例：神经科学专业学生的一个案例研究
The Mysterious Case of Patient X: A Case Study for Neuroscience Students.
作者信息
Ogilvie Judith Mosinger
机构信息
Department of Biology, Saint Louis University, St. Louis, MO 63103.
出版信息
J Undergrad Neurosci Educ. 2019 Dec 21;18(1):C1-C4. eCollection 2019 Fall.
Abstract
The Mysterious Case of Patient X is adapted from an actual clinical case of a famous American writer whose symptoms initially presented as Parkinson's disease. His complex medical history challenges students to investigate alternative diagnoses. Students confront the complexity of biomedical systems from the molecular and cellular processes that underlie neuronal degeneration to the organization and integration of brain regions that control the symptoms of disease. The case is written for upper-level undergraduate or beginning graduate students in biology or neuroscience but could be adapted for introductory neuroscience courses.
摘要
《X 患者的神秘病例》改编自一位美国著名作家的真实临床病例，其症状最初表现为帕金森病。他复杂的病史促使学生去探究其他可能的诊断。学生们要面对生物医学系统的复杂性，从神经元退化背后的分子和细胞过程，到控制疾病症状的脑区的组织与整合。该病例是为生物或神经科学专业的高年级本科生或研究生一年级学生编写的，但也可改编用于神经科学入门课程。
相似文献
1
The Mysterious Case of Patient X: A Case Study for Neuroscience Students.患者X的神秘病例：神经科学专业学生的一个案例研究
J Undergrad Neurosci Educ. 2019 Dec 21;18(1):C1-C4. eCollection 2019 Fall.
2
Impact and educational outcomes of a small group self-directed teaching strategy in a clinical neuroscience curriculum.小组自主教学策略对临床神经科学课程的影响和教育成果。
Anat Sci Educ. 2018 Sep;11(5):478-487. doi: 10.1002/ase.1759. Epub 2017 Dec 18.
3
Two Scientists Share Nobel Prize for the First Time! A Case Study Developed for Exploring the History of Neuroanatomy.两位科学家首次共享诺贝尔奖！为探索神经解剖学史而开发的一个案例研究。
J Undergrad Neurosci Educ. 2019 Jun 30;17(2):C1-C5. eCollection 2019 Spring.
4
Connecting biology and organic chemistry introductory laboratory courses through a collaborative research project.通过一个合作研究项目将生物学与有机化学入门实验室课程联系起来。
Biochem Mol Biol Educ. 2015 Jul-Aug;43(4):233-44. doi: 10.1002/bmb.20871. Epub 2015 Jul 3.
5
The Simpsons Neuron: A Case Study Exploring Neuronal Coding and the Scientific Method for Introductory and Advanced Neuroscience Courses.《辛普森一家》神经元：一个探索神经元编码以及适用于基础和高级神经科学课程的科学方法的案例研究
J Undergrad Neurosci Educ. 2021 Dec 24;20(1):C1-C10. eCollection 2021 Fall.
6
Professor Eric Can't See: A Project-Based Learning Case for Neurobiology Students.埃里克教授看不见：一个面向神经生物学专业学生的基于项目的学习案例。
J Undergrad Neurosci Educ. 2016 Apr 15;15(1):C4-C6. eCollection 2016 Fall.
7
Epilepsy and the Action Potential: Using Case Based Instruction and Primary Literature in a Neurobiology Course.癫痫与动作电位：在神经生物学课程中运用基于案例的教学法和原始文献
J Undergrad Neurosci Educ. 2018 Jun 15;16(2):C7-C10. eCollection 2018 Spring.
8
Development of an Introductory Neuroscience Teaching Experience for Undergraduates with a Low-Cost Neuroscience Summer Academy.通过低成本神经科学暑期学院为本科生开发入门级神经科学教学体验。
J Undergrad Neurosci Educ. 2019 Jun 30;17(2):A125-A129. eCollection 2019 Spring.
9
The National Undergraduate Neuroanatomy Competition: Lessons Learned from Partnering with Students to Innovate Undergraduate Neuroanatomy Education.全国本科生神经解剖学竞赛：与学生合作创新本科生神经解剖学教育的经验教训。
Neuroscientist. 2019 Jun;25(3):271-280. doi: 10.1177/1073858418788000. Epub 2018 Jul 21.
10
Chapter 33: the history of movement disorders.第33章：运动障碍病史。
Handb Clin Neurol. 2010;95:501-46. doi: 10.1016/S0072-9752(08)02133-7.
引用本文的文献
1
Adapting Case Studies for Synchronous and Asynchronous Online Courses.为同步和异步在线课程改编案例研究。
J Undergrad Neurosci Educ. 2022 Jun 1;20(2):A184-A190. doi: 10.59390/NFRQ7249. eCollection 2022 Winter.
2
Virtual/Remote Labs for Fluorescent Immunocytochemistry or Western Blotting: The Next Best Thing to Being There.用于荧光免疫细胞化学或蛋白质印迹的虚拟/远程实验室：身临其境的次优选择。
J Undergrad Neurosci Educ. 2022 Jun 1;20(2):A219-A225. doi: 10.59390/XCGJ3727. eCollection 2022 Winter.
3
Mapping Human Neuronal Diversity in the Search for New Therapeutics: Using Real Human Neuron Data Sets to Build Student Quantitative Skills.在寻找新疗法中绘制人类神经元多样性图谱：利用真实人类神经元数据集培养学生的定量技能。
J Undergrad Neurosci Educ. 2023 Dec 17;22(1):A66-A73. doi: 10.59390/OGTZ5579. eCollection 2023 Fall.
4
Effective Use of Student-Created Case Studies as Assessment in an Undergraduate Neuroscience Course.在本科神经科学课程中有效利用学生创作的案例研究进行评估。
J Undergrad Neurosci Educ. 2021 Jun 20;19(2):A141-A162. eCollection 2021 Spring.
5
Meningitis in College Students: Using a Case Study to Expose Introductory Neuroscience Students to Primary Scientific Literature and Applications of Neuroscience.大学生脑膜炎：通过案例研究让神经科学入门学生接触原始科学文献及神经科学应用
J Undergrad Neurosci Educ. 2020 Jun 28;18(2):C8-C11. eCollection 2020 Spring.
6
JUNE: Continuing to Advance Neuroscience Education in the New Decade.六月：在新的十年中持续推进神经科学教育。
J Undergrad Neurosci Educ. 2019 Dec 21;18(1):E1-E2. eCollection 2019 Fall.
本文引用的文献
1
Professor Eric Can't See: A Project-Based Learning Case for Neurobiology Students.埃里克教授看不见：一个面向神经生物学专业学生的基于项目的学习案例。
J Undergrad Neurosci Educ. 2016 Apr 15;15(1):C4-C6. eCollection 2016 Fall.
2
Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies.神经退行性疾病中错误折叠蛋白的降解：治疗靶点与策略
Exp Mol Med. 2015 Mar 13;47(3):e147. doi: 10.1038/emm.2014.117.
3
Parkinsonian syndromes.帕金森综合征
Continuum (Minneap Minn). 2013 Oct;19(5 Movement Disorders):1189-212. doi: 10.1212/01.CON.0000436152.24038.e0.
4
The use of interrupted case studies to enhance critical thinking skills in biology.运用中断式案例研究提升生物学批判性思维能力
J Microbiol Biol Educ. 2009 Dec 17;10(1):25-31. doi: 10.1128/jmbe.v10.96. Print 2009.
5
Overview of Parkinson's disease.帕金森病概述。
Pharmacotherapy. 2007 Dec;27(12 Pt 2):155S-160S. doi: 10.1592/phco.27.12part2.155S.
6
Diagnosis and management of atypical parkinsonian syndromes.非典型帕金森综合征的诊断与管理
J Neurol Neurosurg Psychiatry. 2002 Mar;72 Suppl 1(Suppl 1):I10-I16. doi: 10.1136/jnnp.72.suppl_1.i10.
7
The neurologic illness of Eugene O'Neill--a clinicopathological report.尤金·奥尼尔的神经疾病——一份临床病理报告。
N Engl J Med. 2000 Apr 13;342(15):1126-33. doi: 10.1056/NEJM200004133421511.
Zotero 插件