Samarai Daniel, Ingemansson Sandra Lindstedt, Gustafsson Ronny, Thilén Ulf, Hlebowicz Joanna
Department of Clinical Sciences, Skåne University Hospital, Lund University, SE-221 85, Lund, Sweden.
Department of Cardiology, Skåne University Hospital, Lund University, SE-221 85, Lund, Sweden.
Cardiovasc Ultrasound. 2020 Jan 27;18(1):4. doi: 10.1186/s12947-020-0186-7.
The aim of this retrospective study was to evaluate the relationship between right ventricular function derived from cardiac magnetic resonance imaging (CMR), echocardiography and exercise stress test performance, NT-proBNP (N-terminal proB-type natriuretic peptide) level and NYHA class in patients with a systemic right ventricle.
All patients with congenitally corrected transposition of the great arteries (ccTGA), or transposition of the great arteries after Mustard or Senning procedures, (TGA) followed at our centre who had undergone CMR, echocardiography, an exercise stress test and blood sampling, were included in the study.
We examined 11 patients (six after the Senning procedure, one after the Mustard procedure, and four ccTGA) who have a median age of 32 years (22-67 years). A significant correlation was observed between the systemic ventricular function, expressed as the CMR-derived right ventricular ejection fraction and the right ventricular global longitudinal strain (r= -0.627; p=0.039).
We have demonstrated that in patients with ccTGA or TGA right ventricular global longitudinal strain may be useful in the evaluation of the systemic right ventricular function.
本回顾性研究旨在评估心脏磁共振成像（CMR）、超声心动图所测右心室功能与运动负荷试验表现、N末端B型利钠肽原（NT-proBNP）水平及纽约心脏协会（NYHA）心功能分级在系统性右心室患者中的关系。
纳入在我们中心接受随访的所有大动脉转位矫正术（ccTGA）患者，或Mustard或Senning术后大动脉转位（TGA）患者，这些患者均接受了CMR、超声心动图、运动负荷试验及血样采集。
我们研究了11例患者（6例接受Senning术，1例接受Mustard术，4例ccTGA），中位年龄为32岁（22 - 67岁）。以CMR所测右心室射血分数及右心室整体纵向应变表示的系统性心室功能之间存在显著相关性（r = -0.627；p = 0.039）。
我们证明，在ccTGA或TGA患者中，右心室整体纵向应变可能有助于评估系统性右心室功能。
