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与饮用能量饮料相关的急性肾损伤和肝炎:一例报告

Acute kidney injury and hepatitis associated with energy drink consumption: a case report.

作者信息

Al Yacoub Raed, Luczkiewicz Debra, Kerr Christopher

机构信息

Division of Hospital Medicine, Department of Internal Medicine, University of Florida, 1230 SW 11th Ave, C405, Gainesville, FL, 32601, USA.

Division of Geriatric and Palliative care, Department of Internal Medicine, University at Buffalo, Buffalo, NY, USA.

出版信息

J Med Case Rep. 2020 Jan 29;14(1):23. doi: 10.1186/s13256-019-2340-0.

Abstract

INTRODUCTION

In the USA, energy drinks are commonly consumed among adults. The side effects of these drinks are not well studied but consumers have reported multiple adverse events to the US Food and Drug Administration including acute kidney injury and acute hepatitis.

CASE PRESENTATION

A 62-year-old white woman presented with progressive weakness, fatigue, confusion, and delirium secondary to acute kidney injury and acute hepatitis associated with excessive energy drink use. Clinical improvement occurred with supportive care and discontinuation of energy drinks, with resolution of acute kidney injury and progressive improvement of liver function. The defined mechanism of injury is unknown but thought due to energy drink ingredients.

CONCLUSION

Multiple cases of energy drink-induced acute kidney injury or acute hepatitis are reported in the literature but this case is the first to report them simultaneously. Ingredients and presumed doses to cause these events are outlined in this case report.

摘要

引言

在美国,能量饮料在成年人中普遍饮用。这些饮料的副作用尚未得到充分研究,但消费者已向美国食品药品监督管理局报告了多起不良事件,包括急性肾损伤和急性肝炎。

病例介绍

一名62岁的白人女性因过量饮用能量饮料导致急性肾损伤和急性肝炎,出现进行性虚弱、疲劳、意识模糊和谵妄。通过支持治疗和停用能量饮料,临床症状得到改善,急性肾损伤得到缓解,肝功能逐渐好转。损伤的确切机制尚不清楚,但认为与能量饮料的成分有关。

结论

文献中报道了多例能量饮料引起的急性肾损伤或急性肝炎病例,但本病例是首例同时报告这两种情况的。本病例报告概述了导致这些事件的成分和推测剂量。

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本文引用的文献

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Energy drink-induced acute kidney injury.能量饮料诱发的急性肾损伤。
Ann Pharmacother. 2014 Oct;48(10):1366-70. doi: 10.1177/1060028014541997. Epub 2014 Jul 1.
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"Vodka energy": too much for the adolescent nephron?"伏特加能量饮料":对青少年的肾脏有害?
Pediatrics. 2011 Jul;128(1):e227-31. doi: 10.1542/peds.2010-2677. Epub 2011 Jun 13.
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Energy beverages: content and safety.能量饮料:成分与安全性。
Mayo Clin Proc. 2010 Nov;85(11):1033-41. doi: 10.4065/mcp.2010.0381.
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Review article: drug hepatotoxicity.综述文章:药物肝毒性
Aliment Pharmacol Ther. 2007 May 15;25(10):1135-51. doi: 10.1111/j.1365-2036.2007.03307.x.
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Accumulation of taurine in patients with renal failure.肾衰竭患者体内牛磺酸的蓄积。
Nephrol Dial Transplant. 2002 Mar;17(3):528-9. doi: 10.1093/ndt/17.3.528.

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