Serrano Norma, Villa-Roel Cristina, Gamboa-Delgado Edna Magaly, Barrera Juan Guillermo, Quintero-Lesmes Doris Cristina
Fundación Cardiovascular de Colombia-FCV, Floridablanca, Santander, Colombia.
Department of Emergency Medicine, University of Alberta, Edmonton, Alberta, Canadá.
Transl Pediatr. 2019 Dec;8(5):363-370. doi: 10.21037/tp.2019.04.04.
Metabolic syndrome (MS) is one of the conditions that increase the risk of developing cardiovascular diseases (CVD) and type-2 diabetes in the early future if it appears during childhood or adolescence. The purpose of the study to compare the MS prevalence of MS estimated in a representative sample of school-age population in Bucaramanga, Colombia, and the MS prevalence estimated in a subsample from the same population in the adolescent stage.
An analytical cross-sectional survey (in the adolescent stage) (n=494) was carried out, nested in a population-based cohort assembled when children were of school age (n=1,282). Selection employed a bi-stage randomized sampling per neighborhoods and houses across the city. Sociodemographic and anthropometric variables, as well as cardiometabolic factors were analyzed in accordance with their distribution, and statistical significance tests were applied according to each case. MS was determined using the Adult Treatment Panel III (ATP III) and International Diabetes Federation (IDF) criteria.
Estimated MS prevalence in school age according to the ATP III criteria was 9.5% (95% CI: 8.0-11.3%) and according to the IDF criteria it was 8.0% (95% CI: 6.6-9.7%). At the time of follow up the prevalence of MS was 13.2% and 14.8% according to the ATP III and IDF criteria, respectively.
MS prevalence of MS increased in 4% from the school age (9.5%) to the adolescence (13.1%).
代谢综合征(MS)是一种若在儿童期或青少年期出现,会增加未来早期发生心血管疾病(CVD)和2型糖尿病风险的病症。本研究旨在比较在哥伦比亚布卡拉曼加市学龄人口代表性样本中估算的MS患病率,以及在同一人群青少年阶段子样本中估算的MS患病率。
开展了一项分析性横断面调查(在青少年阶段)(n = 494),该调查嵌套于当儿童处于学龄期时组建的基于人群的队列研究(n = 1282)。采用两阶段随机抽样,在全市各街区和房屋中进行选择。根据社会人口统计学和人体测量学变量以及心脏代谢因素的分布进行分析,并针对每种情况应用统计显著性检验。采用成人治疗小组第三次报告(ATP III)和国际糖尿病联盟(IDF)标准确定MS。
根据ATP III标准,学龄期MS患病率估计为9.5%(95%置信区间:8.0 - 11.3%),根据IDF标准为8.0%(95%置信区间:6.6 - 9.7%)。随访时,根据ATP III和IDF标准,MS患病率分别为13.2%和14.8%。
MS患病率从学龄期(9.5%)到青少年期(13.1%)增加了4%。