Cribier B
Clinique dermatologique, Hôpitaux universitaires et université de Strasbourg, 1, place de l'Hôpital, 67091 Strasbourg Cedex, France.
Ann Dermatol Venereol. 2019 Dec;146(12S3):12S67-12S75. doi: 10.1016/S0151-9638(20)30016-8.
Atopic dermatitis is associated with an increased risk of asthma (10 to 30% according to age), allergic rhinitis and conjunctivitis and food allergy. Other comorbidiies are globally lest frequent than in psoriasis. There is no increased risk of solid cancer. Smoking is a major confounding factor that has to be taken into account. Obesity and metabolic syndrome are more frequent and there is a moderately increased cardiovascular risk in severe forms of atopic dermatitis. There is a clear-cut increased risk of vitiligo and alopecia areata and a lower risk of other auto-immune diseases, including type I diabetes in children. There is a higher risk of cutaneous but not extra-cutaneous bacterial and viral infections, and increased frequency of contact dermatitis and urticaria. Severe atopic dermatitis is associated with psychiatric comorbidities, like attention disorders/hyperactivity, depression and suicidal ideas. © 2019 Elsevier Masson SAS. All rights reserved.
特应性皮炎与哮喘风险增加相关（根据年龄，风险为10%至30%）、过敏性鼻炎、结膜炎和食物过敏。总体而言，其他合并症的发生率低于银屑病。实体癌风险未增加。吸烟是一个必须考虑的主要混杂因素。肥胖和代谢综合征更为常见，重度特应性皮炎患者的心血管风险适度增加。白癜风和斑秃的风险明显增加，而包括儿童I型糖尿病在内的其他自身免疫性疾病风险较低。皮肤细菌和病毒感染风险较高，但非皮肤感染风险不高，接触性皮炎和荨麻疹的发生率增加。重度特应性皮炎与精神合并症相关，如注意力障碍/多动、抑郁和自杀念头。© 2019爱思唯尔马松出版社。保留所有权利。
