Department of Applied Chemistry, Government College University, Faisalabad 38030-Pakistan.
Department of Applied Chemistry, Government College University, Faisalabad 38030-Pakistan.
Int J Biol Macromol. 2020 May 1;150:289-303. doi: 10.1016/j.ijbiomac.2020.01.265. Epub 2020 Jan 28.
Hydroxyethylcellulose (HEC) is a biocompatible, biodegradable, nontoxic, hydrophilic, non- ionic water soluble derivative of cellulose. It is broadly used in biomedical field, paint industry, as a soil amendment in agriculture, coal dewatering, cosmetics, absorbent pads, wastewater treatment and gel electrolyte membranes. Industrial uses of HEC can be extended by the its grafting with different polymers including poly acrylic acid, polyacrylamide, polylactic acid, polyethyleneglycol, polydimethyleamide, polycaprolactone, polylactic acid and dimethylamino ethylmethacrylate. This permits the formation of new biomaterials with improved properties and versatile applications. In this article, a comprehensive overview of graft copolymers of HEC with other polymers/compounds and their applications in drug delivery, stimuli sensitive hydrogels, super absorbents, personal hygiene products and coal dewatering is presented.
羟乙基纤维素(HEC)是一种生物相容性、可生物降解、无毒、亲水性、非离子水溶性纤维素衍生物。它被广泛应用于生物医药领域、涂料行业、农业中的土壤改良剂、煤炭脱水、化妆品、吸收垫、废水处理和凝胶电解质膜。通过与不同聚合物(包括聚丙烯酸、聚丙烯酰胺、聚乳酸、聚乙二醇、聚二甲基酰胺、聚己内酯、聚乳酸和二甲基氨基乙基甲基丙烯酸酯)接枝,可以扩展 HEC 的工业用途。这允许形成具有改进性能和多功能应用的新型生物材料。本文综述了 HEC 与其他聚合物/化合物的接枝共聚物及其在药物传递、刺激响应水凝胶、高吸水性聚合物、个人卫生用品和煤炭脱水方面的应用。