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核心技术专利：CN118964589B侵权必究
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生物质聚合物的药物应用：当前研究与展望综述

Pharmaceutical Applications of Biomass Polymers: Review of Current Research and Perspectives.

作者信息

Bejenaru Cornelia, Radu Antonia, Segneanu Adina-Elena, Biţă Andrei, Ciocîlteu Maria Viorica, Mogoşanu George Dan, Bradu Ionela Amalia, Vlase Titus, Vlase Gabriela, Bejenaru Ludovic Everard

机构信息

Department of Pharmaceutical Botany, Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, 2 Petru Rareş Street, 200349 Craiova, Dolj, Romania.

Institute for Advanced Environmental Research, West University of Timişoara (ICAM-WUT), 4 Oituz Street, 300086 Timişoara, Timiş, Romania.

出版信息

Polymers (Basel). 2024 Apr 23;16(9):1182. doi: 10.3390/polym16091182.

DOI:10.3390/polym16091182
PMID:38732651
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11085205/
Abstract

Polymers derived from natural biomass have emerged as a valuable resource in the field of biomedicine due to their versatility. Polysaccharides, peptides, proteins, and lignin have demonstrated promising results in various applications, including drug delivery design. However, several challenges need to be addressed to realize the full potential of these polymers. The current paper provides a comprehensive overview of the latest research and perspectives in this area, with a particular focus on developing effective methods and efficient drug delivery systems. This review aims to offer insights into the opportunities and challenges associated with the use of natural polymers in biomedicine and to provide a roadmap for future research in this field.

摘要

源自天然生物质的聚合物因其多功能性已成为生物医学领域的宝贵资源。多糖、肽、蛋白质和木质素在包括药物递送设计在内的各种应用中已显示出有前景的结果。然而，要充分发挥这些聚合物的潜力，还需要应对若干挑战。本文全面概述了该领域的最新研究和观点，特别侧重于开发有效的方法和高效的药物递送系统。本综述旨在深入探讨与在生物医学中使用天然聚合物相关的机遇和挑战，并为该领域的未来研究提供路线图。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/2165baf4c0d0/polymers-16-01182-g024.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/25c5721a3aad/polymers-16-01182-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/4f1eb3e4bcde/polymers-16-01182-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/1fd6f47921a7/polymers-16-01182-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/99851a0636f0/polymers-16-01182-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/25a66dffe293/polymers-16-01182-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/4bcac8b0433a/polymers-16-01182-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/529ab8609bc2/polymers-16-01182-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/d73688bf77f3/polymers-16-01182-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/14db176f80c3/polymers-16-01182-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/1889ce26c2ca/polymers-16-01182-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/8d19604db047/polymers-16-01182-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/9dd70f4eb8fc/polymers-16-01182-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/0b7561a1ca50/polymers-16-01182-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/cbd865e7a2af/polymers-16-01182-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/a3d9a4d2b202/polymers-16-01182-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/70bc1e9ff6eb/polymers-16-01182-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/526476882160/polymers-16-01182-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/e80d818aefed/polymers-16-01182-g018.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/b4768f23d04b/polymers-16-01182-g019.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/d0c93dd92c74/polymers-16-01182-g020.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/428ca4c80a64/polymers-16-01182-g021.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/0173c2572257/polymers-16-01182-g022.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/fd087379ab4e/polymers-16-01182-g023.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/2165baf4c0d0/polymers-16-01182-g024.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/25c5721a3aad/polymers-16-01182-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/4f1eb3e4bcde/polymers-16-01182-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/1fd6f47921a7/polymers-16-01182-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/99851a0636f0/polymers-16-01182-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/25a66dffe293/polymers-16-01182-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/4bcac8b0433a/polymers-16-01182-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/529ab8609bc2/polymers-16-01182-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/d73688bf77f3/polymers-16-01182-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/14db176f80c3/polymers-16-01182-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/1889ce26c2ca/polymers-16-01182-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/8d19604db047/polymers-16-01182-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/9dd70f4eb8fc/polymers-16-01182-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/0b7561a1ca50/polymers-16-01182-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/cbd865e7a2af/polymers-16-01182-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/a3d9a4d2b202/polymers-16-01182-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/70bc1e9ff6eb/polymers-16-01182-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/526476882160/polymers-16-01182-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/e80d818aefed/polymers-16-01182-g018.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/b4768f23d04b/polymers-16-01182-g019.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/d0c93dd92c74/polymers-16-01182-g020.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/428ca4c80a64/polymers-16-01182-g021.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/0173c2572257/polymers-16-01182-g022.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/fd087379ab4e/polymers-16-01182-g023.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153c/11085205/2165baf4c0d0/polymers-16-01182-g024.jpg

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[1]
Developing natural polymers for skin wound healing.

Bioact Mater. 2023-11-26

[2]
Degradable Polymeric Bio(nano)materials and Their Biomedical Applications: A Comprehensive Overview and Recent Updates.

Polymers (Basel). 2024-1-10

[3]
Preparation and evaluation of luteolin-loaded PLA-based shape memory gastroretentive drug delivery systems.

Int J Pharm. 2024-1-25

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Applications of guar gum polysaccharide for pharmaceutical drug delivery: A review.

Int J Biol Macromol. 2024-2

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Natural and Synthetic Polymeric Biomaterials for Application in Wound Management.

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Recent Advances in Biodegradable and Biocompatible Synthetic Polymers Used in Skin Wound Healing.

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[10]
An Accessible Method to Improve the Stability and Reusability of Porcine Pancreatic α-Amylase via Immobilization in Gellan-Based Hydrogel Particles Obtained by Ionic Cross-Linking with Mg Ions.

Molecules. 2023-6-11

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