Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.
Department of Dermatology, University Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.
Adv Mater. 2020 Mar;32(11):e1908008. doi: 10.1002/adma.201908008. Epub 2020 Feb 3.
Durable and biocompatible superhydrophobic surfaces are of significant potential use in biomedical applications. Here, a nonfluorinated, elastic, superhydrophobic film that can be used for medical wound dressings to enhance their hemostasis function is introduced. The film is formed by titanium dioxide nanoparticles, which are chemically crosslinked in a poly(dimethylsiloxane) (PDMS) matrix. The PDMS crosslinks result in large strain elasticity of the film, so that it conforms to deformations of the substrate. The photocatalytic activity of the titanium dioxide provides surfaces with both self-cleaning and antibacterial properties. Facile coating of conventional wound dressings is demonstrated with this composite film and then resulting improvement for hemostasis. High gas permeability and water repellency of the film will provide additional benefit for medical applications.
耐用且生物相容的超疏水表面在生物医学应用中具有重要的潜在用途。在这里，介绍了一种非氟化的弹性超疏水薄膜，可用于医疗伤口敷料以增强其止血功能。该薄膜由二氧化钛纳米粒子组成，这些纳米粒子在聚二甲基硅氧烷（PDMS）基质中通过化学交联形成。PDMS 交联使薄膜具有大应变弹性，从而使其能够适应基底的变形。二氧化钛的光催化活性为表面提供了自清洁和抗菌性能。通过这种复合薄膜，可以很容易地对传统的伤口敷料进行涂层，从而改善其止血效果。该薄膜具有高气密性和拒水性，这将为医疗应用带来额外的益处。
