牙周病及其预防，传统与新途径
Periodontal disease and its prevention, by traditional and new avenues.
作者信息
Mann Jonathan, Bernstein Yaron, Findler Moti
机构信息
Department of Community Dentistry, Faculty of Dental Medicine, Hebrew University-Hadassah School of Dental Medicine, 91120 Jerusalem, Israel.
MACCABIDENT-Dental Health Service, 6801298 Tel Aviv, Israel.
出版信息
Exp Ther Med. 2020 Feb;19(2):1504-1506. doi: 10.3892/etm.2019.8381. Epub 2019 Dec 27.
Abstract
One of the most prevalent diseases affecting humans are those which affect the oral cavity. Several diseases can affect the mouth, such as oral cancer, dental caries, Lichen Planus and, of course, periodontal disease with its variants. This review discusses gingivitis, periodontitis and peri-implantitis with a brief focus on the different primary prevention aids, such as mechanical, chemical and the new generation of potential products to be used in the future dental market, products that are prepared from natural sources, the general trend worldwide. In this review, not all new inventions will be mentioned, yet, the role of aged garlic extract (AGE) will be described in addition to a new toothpaste which originates from the Dead Sea and the Purecare dental which produces the Ozone (H3) for the prevention of periodontal disease.
摘要
影响人类的最常见疾病之一是那些影响口腔的疾病。有几种疾病会影响口腔，如口腔癌、龋齿、扁平苔藓，当然还有牙周病及其变体。本综述讨论了牙龈炎、牙周炎和种植体周围炎，并简要关注了不同的一级预防辅助手段，如机械、化学以及未来牙科市场将使用的新一代潜在产品、天然来源制备的产品、全球总体趋势。在本综述中，不会提及所有新发明，但除了一种源自死海的新牙膏和生产用于预防牙周病的臭氧（H3）的Purecare牙科产品外，还将描述 aged garlic extract（AGE）的作用。
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本文引用的文献
1
The Efficacy of Aged Garlic Extract on Gingivitis - A Randomized Clinical Trial. aged garlic extract对牙龈炎的疗效——一项随机临床试验
J Clin Dent. 2018 Jun;29(2):52-56.
2
A new classification scheme for periodontal and peri-implant diseases and conditions - Introduction and key changes from the 1999 classification.牙周病和种植体周围病的新分类系统——1999 年分类的介绍和主要变化。
J Clin Periodontol. 2018 Jun;45 Suppl 20:S1-S8. doi: 10.1111/jcpe.12935.
3
Triclosan exposure, transformation, and human health effects.三氯生的暴露、转化及其对人类健康的影响。
J Toxicol Environ Health B Crit Rev. 2017;20(8):447-469. doi: 10.1080/10937404.2017.1399306.
4
Prevalence of periodontal disease, its association with systemic diseases and prevention.牙周病的患病率、其与全身疾病的关联及预防
Int J Health Sci (Qassim). 2017 Apr-Jun;11(2):72-80.
5
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010.2010 年全球疾病负担研究：1990-2010 年 289 种疾病和伤害的 1160 种后遗症导致的残疾生存年数的系统分析。
Lancet. 2012 Dec 15;380(9859):2163-96. doi: 10.1016/S0140-6736(12)61729-2.
6
The epidemiology of peri-implantitis.种植体周围炎的流行病学。
Clin Oral Implants Res. 2012 Oct;23 Suppl 6:67-76. doi: 10.1111/j.1600-0501.2012.02541.x.
7
Strengthening the prevention of periodontal disease: the WHO approach.加强牙周病预防：世卫组织的方法。
J Periodontol. 2005 Dec;76(12):2187-93. doi: 10.1902/jop.2005.76.12.2187.
8
Epidemiology of periodontal disease: a review and clinical perspectives.牙周病流行病学：综述与临床视角
J Int Acad Periodontol. 2001 Jan;3(1):14-21.
9
Gingiva, teeth and sea salt.牙龈、牙齿和海盐。
Am J Dent. 1999 Feb;12(1):5-8.
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