Wang M, Ma J, Pan L, Chen T, Wang H L, Wang Y H, Wang W R, Pan X D, Qian Y G, Zhang X, Zhong Y, Shan G L
Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
School of Medicine, Tsinghua University, Beijing, China.
Eye (Lond). 2019 Nov;33(11):1722-1732. doi: 10.1038/s41433-019-0469-0. Epub 2019 Jun 3.
To assess the prevalence of and risk factors for refractive error (RE) in Han and Mongolian adults aged 40-80 years in Inner Mongolia in China and to identify ethnic differences in RE between these populations.
Our cross-sectional study is part of the China National Health Survey (CNHS). The age-adjusted prevalence of RE in Han and Mongolian adults aged 40-80 in Inner Mongolia were compared. A multivariable logistic regression model was used to identify risk factors.
Among 2090 people, the age-adjusted prevalence of myopia (SE < -0.5D), hyperopia (SE > 0.5D), high myopia (SE < -6.0D) and astigmatism (cylinder ≥ 0.5D) were 29.4% (95% confidence interval (CI), 27.4-31.3%), 28.4% (95% CI, 26.4-30.5%), 3.6% (95% CI, 2.8-4.4%) and 65.9% (95% CI, 63.9-67.9%), respectively. The age-adjusted prevalence of myopia in the Han population was higher than that in the Mongolian population (31.8% vs. 23.0%, p < 0.001), but the prevalence of hyperopia was lower (25.8% vs. 35.3%, p = 0.002). In the multivariable logistic regression, ethnicity was associated with myopia (p = 0.001) and hyperopia (p = 0.001). Myopia was also associated with age, time spent in rural areas (p < 0.001) and middle/high school and undergraduate/graduate education levels (p = 0.027 and p < 0.001, respectively, compared with lower education levels). Additionally, age, height (p = 0.015) and pterygium (p = 0.014) were associated with hyperopia.
Ethnicity is closely related to RE in Inner Mongolia in mainland China. Our study investigates differences in prevalence of and risk factors for RE between the Han and Mongolian populations, which could not be explained by differences in the risk factors investigated in this study.
评估中国内蒙古地区40 - 80岁汉族和蒙古族成年人屈光不正(RE)的患病率及危险因素,并确定这些人群之间屈光不正的种族差异。
我们的横断面研究是中国国家健康调查(CNHS)的一部分。比较了内蒙古40 - 80岁汉族和蒙古族成年人年龄调整后的屈光不正患病率。使用多变量逻辑回归模型确定危险因素。
在2090人中,近视(球镜等效度(SE)< -0.5D)、远视(SE>0.5D)、高度近视(SE< -6.0D)和散光(柱镜≥0.5D)的年龄调整患病率分别为29.4%(95%置信区间(CI),27.4 - 31.3%)、28.4%(95% CI,26.4 - 30.5%)、3.6%(95% CI,2.8 - 4.4%)和65.9%(95% CI,63.9 - 67.9%)。汉族人群中近视的年龄调整患病率高于蒙古族人群(31.8%对23.0%,p<0.001),但远视患病率较低(25.8%对35.3%,p = 0.002)。在多变量逻辑回归中,种族与近视(p = 0.001)和远视(p = 0.001)相关。近视还与年龄、在农村地区度过的时间(p<0.001)以及初中/高中和本科/研究生教育水平相关(与较低教育水平相比,p分别为0.027和p<0.001)。此外,年龄、身高(p = 0.015)和翼状胬肉(p = 0.014)与远视相关。
在中国内蒙古地区,种族与屈光不正密切相关。我们的研究调查了汉族和蒙古族人群之间屈光不正患病率及危险因素的差异,这些差异无法用本研究中所调查的危险因素差异来解释。