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The many metabolic sources of acetyl-CoA to support histone acetylation and influence cancer progression.

作者信息

Feron Olivier

机构信息

Pole of Pharmacology and Therapeutics (FATH), Institut de Recherche Expérimentale et Clinique (IREC), UCLouvain, Brussels, Belgium.

出版信息

Ann Transl Med. 2019 Dec;7(Suppl 8):S277. doi: 10.21037/atm.2019.11.140.

DOI:10.21037/atm.2019.11.140
PMID:32015996
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6976516/
Abstract
摘要

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Curr Opin Clin Nutr Metab Care. 2019 Nov;22(6):427-433. doi: 10.1097/MCO.0000000000000601.
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Nuclear Glycogenolysis Modulates Histone Acetylation in Human Non-Small Cell Lung Cancers.核糖原分解调节人非小细胞肺癌中的组蛋白乙酰化。
Cell Metab. 2019 Nov 5;30(5):903-916.e7. doi: 10.1016/j.cmet.2019.08.014. Epub 2019 Sep 12.
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Phase I/Ib Study of Pembrolizumab Plus Vorinostat in Advanced/Metastatic Non-Small Cell Lung Cancer.帕博利珠单抗联合伏立诺他治疗晚期/转移性非小细胞肺癌的 I/ Ib 期研究。
Clin Cancer Res. 2019 Nov 15;25(22):6623-6632. doi: 10.1158/1078-0432.CCR-19-1305. Epub 2019 Aug 13.
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Acetylation & Co: an expanding repertoire of histone acylations regulates chromatin and transcription.乙酰化与伙伴：组蛋白酰化修饰的不断扩展调控染色质和转录。
Essays Biochem. 2019 Apr 23;63(1):97-107. doi: 10.1042/EBC20180061.
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Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis.成纤维细胞动员肿瘤细胞糖原促进增殖和转移。
Cell Metab. 2019 Jan 8;29(1):141-155.e9. doi: 10.1016/j.cmet.2018.08.007. Epub 2018 Aug 30.
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Curr Opin Clin Nutr Metab Care. 2017 Jul;20(4):254-260. doi: 10.1097/MCO.0000000000000381.
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Cancer cell metabolism and mitochondria: Nutrient plasticity for TCA cycle fueling.癌细胞代谢与线粒体：三羧酸循环燃料的营养可塑性。
Biochim Biophys Acta Rev Cancer. 2017 Aug;1868(1):7-15. doi: 10.1016/j.bbcan.2017.01.002. Epub 2017 Jan 18.
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Lipids Reprogram Metabolism to Become a Major Carbon Source for Histone Acetylation.脂质重编程代谢以成为组蛋白乙酰化的主要碳源。
Cell Rep. 2016 Nov 1;17(6):1463-1472. doi: 10.1016/j.celrep.2016.10.012.