Lundgren S
Department of Oral Surgery, University of Umeå, Sweden.
Acta Anaesthesiol Scand Suppl. 1988;88:24-6. doi: 10.1111/j.1399-6576.1988.tb02829.x.
A number of cross-over studies on sedation in outpatient oral surgery investigated the quality of sedation produced by intravenous or rectal administration of diazepam. The sedation methods were equally efficient with a mean dose of 0.24 mg/kg (range 0.1-0.4) for i.v. administration and 0.53 mg/kg (range 0.5-0.6) for rectal administration. Eighty-five per cent of the patients preferred surgery under sedation and local anaesthesia to local anaesthesia alone. The patients preferred the session in which they experienced stronger sedation, regardless of the route of administration.
多项关于门诊口腔手术镇静的交叉研究调查了静脉注射或直肠给药地西泮所产生的镇静效果。镇静方法同样有效，静脉注射的平均剂量为0.24毫克/千克（范围0.1 - 0.4），直肠给药的平均剂量为0.53毫克/千克（范围0.5 - 0.6）。85%的患者更喜欢在镇静和局部麻醉下进行手术，而不是单纯局部麻醉。无论给药途径如何，患者都更喜欢他们体验到更强镇静效果的那一次治疗。
