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奥地利严重流感季节及其对儿科人群的影响:2017 年 11 月至 2018 年 3 月的死亡率和住院率。

A severe influenza season in Austria and its impact on the paediatric population: mortality and hospital admission rates, november 2017 - march 2018.

机构信息

Department of General Paediatrics, Medical University of Graz, Graz, Austria.

Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria.

出版信息

BMC Public Health. 2020 Feb 4;20(1):178. doi: 10.1186/s12889-020-8239-2.

Abstract

BACKGROUND

In Austria paediatric influenza-associated hospitalisations and deaths have never been systematically monitored. We examined the influenza season 2017/18 in terms of hospitalisation and mortality in the Austrian paediatric population and put the results into perspective of the available data from the last 15 years.

METHODS

Cases of influenza-associated hospitalisations and deaths for season 2017/18 in children below 18 years were retrospectively collected from 12 and 33 Austrian hospitals, respectively. Hospitalisation and mortality rates for the whole Austrian paediatric population were estimated, adjusting for the population in each catchment area. Two Austrian databases were queried for hospitalisations and deaths associated with influenza during 2002-2016. Rough estimate of the vaccination coverage was calculated from a survey on 100 inpatients.

RESULTS

Influenza-related paediatric hospitalisation rate in season 2017/18 was estimated as 128 (CI: 122-135) per 100,000 children, much higher than the national average of 40 per 100,000 over the years 2002-2016. There were nine reported influenza-associated deaths among children, resulting in mortality rate of 0.67 (CI: 0.32-1.21) per 100,000 children.

CONCLUSIONS

Reported influenza-associated hospitalisations and fatalities demonstrate a high burden of influenza in the Austrian paediatric population corresponding with very low vaccination coverage.

摘要

背景

在奥地利,儿科流感相关的住院和死亡从未被系统监测过。我们研究了 2017/18 年流感季节中奥地利儿科人群的住院和死亡率,并将结果与过去 15 年的可用数据进行了对比。

方法

从 12 家和 33 家奥地利医院分别回顾性收集了 2017/18 年期间 18 岁以下儿童流感相关住院和死亡病例。通过对每个集水区的人口进行调整,估算了整个奥地利儿科人群的住院和死亡率。对 2002-2016 年期间与流感相关的住院和死亡情况在两个奥地利数据库中进行了查询。通过对 100 名住院患者的调查,估算了疫苗接种覆盖率的粗略估计值。

结果

2017/18 年流感相关儿科住院率估计为每 10 万儿童 128 例(95%CI:122-135),远高于 2002-2016 年期间全国每 10 万儿童 40 例的平均水平。报告有 9 例儿童与流感相关的死亡,导致死亡率为每 10 万儿童 0.67 例(95%CI:0.32-1.21)。

结论

报告的流感相关住院和死亡病例表明,流感在奥地利儿科人群中负担沉重,与非常低的疫苗接种覆盖率相对应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e79e/7001220/1e029114adc8/12889_2020_8239_Fig1_HTML.jpg

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