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B cells and TLSs facilitate a response to ICI.

作者信息

Romero Diana

机构信息

Nature Reviews Clinical Oncology, .

出版信息

Nat Rev Clin Oncol. 2020 Apr;17(4):195. doi: 10.1038/s41571-020-0338-6.

DOI:10.1038/s41571-020-0338-6
PMID:32024979
Abstract
摘要

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B cells and TLSs facilitate a response to ICI.B细胞和三级淋巴结构促进对免疫检查点抑制剂的反应。
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Tertiary lymphoid structures with overlapping histopathologic features of cutaneous marginal zone lymphoma during neoadjuvant cemiplimab therapy are associated with antitumor response.在新辅助西普单抗治疗期间,具有皮肤边缘区淋巴瘤重叠组织病理学特征的三级淋巴结构与抗肿瘤反应相关。
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Tertiary lymphoid structures improve immunotherapy and survival in melanoma.三级淋巴结构可改善黑色素瘤的免疫治疗和生存率。
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B cells! Don't go the wrong way in this tumor.B 细胞!在这个肿瘤里别走错路。
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Multiple mechanisms and applications of tertiary lymphoid structures and immune checkpoint blockade.三级淋巴结构和免疫检查点阻断的多种机制及应用
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B cell c-Maf signaling promotes tumor progression in animal models of pancreatic cancer and melanoma.B 细胞 c-Maf 信号促进胰腺癌和黑色素瘤动物模型中的肿瘤进展。
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The impact of tertiary lymphoid structures on tumor prognosis and the immune microenvironment in non-small cell lung cancer.
三级淋巴结构对非小细胞肺癌肿瘤预后和免疫微环境的影响。
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Heterogeneity of tertiary lymphoid structures in cancer.癌症中的三级淋巴结构异质性。
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Significance of CD103 tissue-resident memory T cells for predicting the effectiveness of immune checkpoint inhibitors in esophageal cancer.CD103 组织驻留记忆 T 细胞对预测食管癌免疫检查点抑制剂疗效的意义。
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IgD ligation allows peritoneal cavity B cell proliferation.IgD 交联可导致腹腔 B 细胞增殖。
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