Department of Natural Science, Lincoln Center, Fordham University, New York, NY.
Photochem Photobiol. 2020 May;96(3):524-528. doi: 10.1111/php.13223. Epub 2020 Mar 5.
Photodynamic therapy [dye-light therapy] is an excellent technique for use in detection and treatment of cancerous tissues. While this therapy is effective, it is limited by the phototoxic reactions that can occur in the surrounding normal tissues. These damaging side effects are of particular importance when treating neurosensory organs, such as the human eye. We report here new treatment strategies to enhance photodynamic effectiveness while limiting side effects to normal tissues.
光动力疗法(染料光疗)是一种用于检测和治疗癌组织的优秀技术。虽然这种疗法很有效,但它受到周围正常组织中可能发生的光毒性反应的限制。在治疗神经感觉器官(如人眼)时,这些破坏性的副作用尤为重要。我们在这里报告了新的治疗策略,以提高光动力的效果,同时将副作用限制在正常组织内。