Veterinary Parasitology, Department of Infection Biology, Institute of Infection and Global Health, University of Liverpool, Institute of Veterinary Science, Chester High Road, Neston CH64 7TE, UK.
Vet Clin North Am Food Anim Pract. 2020 Mar;36(1):145-158. doi: 10.1016/j.cvfa.2019.11.002.
Veterinarians and farmers must contend with the development of drug resistance and climate variability, which threaten the sustainability of current parasite control practices. Field trials evaluating competing strategies for controlling parasites while simultaneously slowing the development of resistance are time consuming and expensive. In contrast, modelling studies can rapidly explore a wide range of scenarios and have generated an array of decision support tools for veterinarians and farmers such as real-time weather-dependent infection risk alerts. Models have also been valuable for predicting the development of anthelmintic resistance, evaluating the sustainability of current parasite control practices and promoting the responsible use of novel anthelmintics.
兽医和农民必须应对耐药性的发展和气候变异性，这威胁到当前寄生虫控制实践的可持续性。评估控制寄生虫的竞争策略同时减缓耐药性发展的田间试验既耗时又昂贵。相比之下，模型研究可以快速探索广泛的场景，并为兽医和农民生成了一系列决策支持工具，例如实时天气相关的感染风险警报。模型对于预测驱虫剂耐药性的发展、评估当前寄生虫控制实践的可持续性以及促进新型驱虫剂的合理使用也很有价值。
