Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
Unit of Endocrinology and Diabetes, Department of Medicine, Campus Bio-Medico University of Rome, Rome, Italy.
Int J Immunopathol Pharmacol. 2019 Jan-Dec;33:2058738419866582. doi: 10.1177/2058738419866582.
Diabetes mellitus (DM) is a widespread disease in our country. Urogenital infections, including urinary tract infections, vaginitis, balanitis, balanoposthitis, and male accessory gland infections, show a higher risk of occurrence in patients with DM that non-diabetic subjects. Both non-drug-related and drug-related mechanisms are involved in their pathogenesis. These conditions may impact on glucose control and islets function in DM and more likely develop into adverse complications. A throughout microbial characterization, including the drug-sensitivity test, is required for a proper management. To reduce the risk of recurrence, combined treatment, including antibiotic, anti-inflammatory, and fibrinolytic molecules, should be prescribed also to the sexual partner. The choice of the antidiabetic drug to prescribe should take into consideration the presence of urogenital infections. In conclusion, urogenital infections may more likely lead to complication in diabetic than non-diabetic patients, affect fertility and glucose control. Therefore, they need proper management.
糖尿病（DM）是我国广泛存在的疾病。与非糖尿病患者相比，糖尿病患者发生尿路感染、阴道炎、包皮炎、包皮龟头炎和男性附属腺感染等泌尿系统感染的风险更高。其发病机制涉及非药物相关和药物相关的机制。这些情况可能会影响 DM 患者的血糖控制和胰岛功能，更容易发展成不良并发症。需要对微生物进行全面特征分析，包括药敏试验，以进行适当的管理。为了降低复发风险，还应向性伴侣开具包括抗生素、抗炎药和纤维蛋白溶解分子在内的联合治疗药物。选择要开具的降糖药物时应考虑是否存在泌尿系统感染。总之，泌尿系统感染可能会使糖尿病患者比非糖尿病患者更容易发生并发症，影响生育和血糖控制。因此，需要进行适当的管理。
