Vienna Reading Center, Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.
Retina. 2020 Dec;40(12):2255-2262. doi: 10.1097/IAE.0000000000002774.
To explore the regional distribution of macular neovascularization type 3 (MNV3).
Seventy-eight eyes of 78 patients were reviewed. We defined the location of each lesion after applying a modified ETDRS grid and the incidence of simultaneous MNV1 or 2. Also, we investigated the distribution of MNV3 at the outline of the foveal avascular zone and when the diameter of foveal avascular zone was less than 325 µm.
The distribution of MNV3 was 4 lesions (5%) from the center to 500 µm, 72 (92%) from 500 µm to 1500 µm, and 2 (3%) from 1,500 µm to 3000 µm. The distribution in respect of the ETDRS fields was 7 (9%) nasal, 16 (20%) superior, 32 (40%) temporal, and 23 (31%) inferior. No additional MNV1 or 2 were found elsewhere. Most lesions tended to distribute along straight bands radiating from the perifoveal area, mainly in the temporal half (72%). None of the cases had MNV3 at the boundary of the foveal avascular zone. Only five cases had foveal avascular zone diameter of less than 325 µm, the closest lesion was 425 µm away from the center.
MNV3 lesions are most likely neither symmetrical nor uniformly distributed. They have a higher affinity to distribute radially in the temporal perifoveal area.
探讨黄斑新生血管 3 型（MNV3）的区域性分布。
回顾了 78 例 78 只眼的资料。我们在应用改良 ETDRS 网格后定义了每个病变的位置，并记录同时存在 MNV1 或 2 的发生率。此外，我们还研究了 MNV3 在中心凹无血管区轮廓处以及当中心凹无血管区直径小于 325 µm 时的分布情况。
MNV3 的分布情况为：中心至 500 µm 处有 4 个病变（5%），500 µm 至 1500 µm 处有 72 个病变（92%），1500 µm 至 3000 µm 处有 2 个病变（3%）。按 ETDRS 视野分布，鼻侧有 7 个病变（9%），上侧有 16 个病变（20%），颞侧有 32 个病变（40%），下侧有 23 个病变（31%）。在其他部位未发现额外的 MNV1 或 2。大多数病变倾向于沿从中心凹旁区发出的直带分布，主要位于颞侧（72%）。没有病例在中心凹无血管区边界处发现 MNV3。仅有 5 例中心凹无血管区直径小于 325 µm，最近的病变距离中心 425 µm。
MNV3 病变既不对称也不均匀分布。它们更倾向于在颞侧中心凹旁区呈放射状分布。
