College of Health Solutions, Arizona State University, Tempe, AZ, USA; College of Health Sciences, Midwestern University, Glendale, AZ, USA.
College of Health Solutions, Arizona State University, Tempe, AZ, USA.
Brain Lang. 2020 Apr;203:104756. doi: 10.1016/j.bandl.2020.104756. Epub 2020 Feb 4.
Non-canonical sentence comprehension impairments are well-documented in aphasia. Studies of neurotypical controls indicate that prosody can aid comprehension by facilitating attention towards critical pitch inflections and phrase boundaries. However, no studies have examined how prosody may engage specific cognitive and neural resources during non-canonical sentence comprehension in persons with left hemisphere damage. Experiment 1 examines the relationship between comprehension of non-canonical sentences spoken with typical and atypical prosody and several cognitive measures in 25 persons with chronic left hemisphere stroke and 20 matched controls. Experiment 2 explores the neural resources critical for non-canonical sentence comprehension with each prosody type using region-of-interest-based multiple regressions. Lower orienting attention abilities and greater inferior frontal and parietal damage predicted lower comprehension, but only for sentences with typical prosody. Our results suggest that typical sentence prosody may engage attention resources to support non-canonical sentence comprehension, and this relationship may be disrupted following left hemisphere stroke.
非典型句子理解障碍在失语症中已有充分记录。对神经典型对照的研究表明，韵律可以通过促进对关键音高转折和短语边界的注意力来帮助理解。然而，尚无研究探讨在左半球损伤患者的非典型句子理解过程中，韵律如何利用特定的认知和神经资源。实验 1 研究了 25 名慢性左半球中风患者和 20 名匹配对照者在理解具有典型和非典型韵律的非典型句子时与几种认知测量之间的关系。实验 2 使用基于感兴趣区域的多元回归探讨了每种韵律类型对非典型句子理解至关重要的神经资源。较低的定向注意力能力和更大的下额叶和顶叶损伤预测理解能力较低，但仅适用于具有典型韵律的句子。我们的结果表明，典型句子韵律可能会利用注意力资源来支持非典型句子理解，而这种关系在左半球中风后可能会受到干扰。
