Odusanya Benjamin Olasunkanmi, Pearce Ian, Modgil Vaibhav
Bolton NHS Foundation Trust, Bolton, UK.
Manchester University NHS Foundation Trust and University of Manchester, Manchester, UK.
Int J Impot Res. 2024 Mar 14. doi: 10.1038/s41443-024-00860-3.
POIS is a rare condition characterized by multisystem symptoms with unclear aetiology. Various attempts have been made to characterize this condition and knowledge is still evolving regarding its aetiology and effective treatment. We have summarized the findings in the English language literature for this rare condition. PubMed search was performed and over 300 English language articles which were screened for relevance. 34 articles were deemed suitable for inclusion. POIS occurs in age range of 21-61 years. Onset of symptoms is usually within 45 min and lasts for an average of 7 days. Primary POIS accounts for approximately half of the cases in literature. The three commonest symptoms were fatigue (68.7), poor concentration (63.9%) and irritation (51.9%). Treatments with variable efficacy which have been proposed include hyposensitisation, antihistamines, alpha blockers, NSAIDS and testosterone replacements. POIS is an important condition which affects the quality of life of men. It is vital that it is managed on a sound scientific basis.
POIS是一种罕见疾病，其特征为多系统症状，病因不明。人们已进行了各种尝试来对这种疾病进行特征描述，关于其病因和有效治疗方法的认识仍在不断发展。我们总结了英文文献中关于这种罕见疾病的研究结果。进行了PubMed检索，筛选出300多篇相关英文文章。34篇文章被认为适合纳入。POIS发病年龄在21至61岁之间。症状通常在45分钟内出现，平均持续7天。原发性POIS在文献报道的病例中约占一半。最常见的三种症状是疲劳（68.7%）、注意力不集中（63.9%）和易怒（51.9%）。已提出的疗效各异的治疗方法包括减敏疗法、抗组胺药、α受体阻滞剂、非甾体抗炎药和睾酮替代疗法。POIS是一种影响男性生活质量的重要疾病。在坚实的科学基础上对其进行管理至关重要。
