Rosetti Leah, Kanani Amin, Witherspoon Luke, Flannigan Ryan, Elliott Stacy
Department of Psychiatry, University of British Columbia, 255 Wesbrook Mall, Vancouver, BC V6T 2A1, Canada.
Division of Allergy and Immunology, Department of Medicine, University of British Columbia, St. Paul's Hospital, 1081 Burrard Street, Room 166, Vancouver, BC V6Z 1Y6, Canada.
Sex Med. 2023 Mar 2;11(2):qfac021. doi: 10.1093/sexmed/qfac021. eCollection 2023 Apr.
Postorgasmic illness syndrome (POIS) is a rare condition in which individuals develop generalized and flu-like symptoms after ejaculation. Several mechanisms and treatments for this disorder have been proposed but many questions remain.
We sought to present a summary of literature to date and highlight common symptoms, associated features, comorbidities, and laboratory findings in a clinical sample of patients with POIS.
We conducted a retrospective chart review of 6 patients with POIS in our clinic and presented compiled results.
We identified newly described non-flu-like presentations, onset of symptoms with high states of arousal without ejaculation, and presence of psychiatric comorbidity in a majority of patients. We did not identify a postorgasm allergic response with bloodwork available.
POIS remains a poorly understood condition that likely comprises a number of different clinical entities. Further research on a larger clinical sample is necessary to better characterize POIS and understand its biological and psychological basis.
射精后疾病综合征（POIS）是一种罕见病症，患者在射精后会出现全身性类似流感的症状。针对这种病症已提出了多种机制和治疗方法，但仍存在许多问题。
我们试图总结迄今为止的文献，并强调POIS临床样本患者的常见症状、相关特征、合并症和实验室检查结果。
我们对诊所中6例POIS患者进行了回顾性病历审查，并展示汇总结果。
我们发现了新描述的非流感样表现、在高度兴奋但未射精时出现症状，以及大多数患者存在精神合并症。通过现有血液检查未发现射精后过敏反应。
POIS仍然是一种了解不足的病症，可能包含多种不同的临床实体。需要对更大临床样本进行进一步研究，以更好地界定POIS并了解其生物学和心理学基础。
