Bacon W H, Krieger J, Turlot J C, Stierle J L
Université Louis Pasteur, Strasbourg, France.
Cleft Palate J. 1988 Oct;25(4):374-8.
Obstructive sleep apneas syndrome (OSAS) has been associated with a clinical reduction of the pharyngeal spaces. To define whether predisposing skeletal craniofacial conditions exist in OSAS patients, 32 OSAS adult patients were compared in a cephalometric investigation with a control sample of 40 adults with ideal dentofacial traits. A t-test assessed the statistical significance of the differences in the two groups; correlation matrix tabulation and discriminant function analysis helped in the identification of the influence of different variables in segregation of the two populations. The following observations were made: There were no differences in maxillary or mandibular prognathism between the two groups. The sagittal dimension of the cranial base was significantly reduced in the OSAS sample, as was the bony pharyngeal opening and maxillary length. This posterior facial compression was associated with increased lower face height (p less than 0.01 in all cases). There were significant correlations in both groups between cranial base length or angulation and pharyngeal opening (p less than 0.01). Eighty percent of the population was correctly sorted out using the discriminant function analysis, with only eight controls and five OSAS patients misclassified. However, this analysis suggested that factors other than the cephalometric may be involved in OSAS.
阻塞性睡眠呼吸暂停综合征（OSAS）与咽腔空间的临床缩小有关。为了确定OSAS患者是否存在易患的骨骼颅面状况，在一项头影测量研究中，对32例成年OSAS患者与40例具有理想牙颌面特征的成年对照样本进行了比较。t检验评估了两组差异的统计学意义；相关矩阵列表和判别函数分析有助于确定不同变量在区分这两个人群中的影响。得出以下观察结果：两组之间上颌或下颌前突无差异。OSAS样本中颅底的矢状径显著减小，骨性咽口和上颌长度也显著减小。这种面部后部受压与面下高度增加有关（所有病例p均小于0.01）。两组中颅底长度或角度与咽口之间均存在显著相关性（p小于0.01）。使用判别函数分析，80%的人群被正确分类，只有8例对照和5例OSAS患者被错误分类。然而，该分析表明，除头影测量因素外，其他因素可能也与OSAS有关。
