Pasco Julie A, Stuart Amanda L, Holloway-Kew Kara L, Tembo Monica C, Sui Sophia X, Anderson Kara B, Hyde Natalie K, Williams Lana J, Kotowicz Mark A
School of Medicine, Deakin University, Geelong, VIC, 3220, Australia.
Department of Medicine - Western Health, The University of Melbourne, St Albans, Australia.
BMC Musculoskelet Disord. 2020 Feb 8;21(1):89. doi: 10.1186/s12891-020-3098-7.
The extent of muscle deterioration associated with ageing or disease can be quantified by comparison with appropriate reference data. The objective of this study is to present normative data for lower-limb muscle strength and quality for 573 males and 923 females aged 20-97 yr participating in the Geelong Osteoporosis Study in southeastern Australia.
In this cross-sectional study, measures of muscle strength for hip flexors and hip abductors were obtained using a Nicholas manual muscle tester, a hand-held dynamometer (HHD; kg). Leg lean mass was measured by dual energy x-ray absorptiometry (DXA; kg), and muscle quality calculated as strength/mass (N/kg).
For both sexes, muscle strength and quality decreased with advancing age. Age explained 12.9-25.3% of the variance in muscle strength in males, and 20.8-24.6% in females; age explained less of the variance in muscle quality. Means and standard deviations for muscle strength and quality for each muscle group are reported by age-decade for each sex, and cutpoints equivalent to T-scores of - 2.0 and - 1.0 were derived using data from young males (n = 89) and females (n = 148) aged 20-39 years.
These data will be useful for quantifying the extent of dynapenia and poor muscle quality among adults in the general population in the face of frailty, sarcopenia and other age-related muscle dysfunction.
与衰老或疾病相关的肌肉退化程度可通过与适当的参考数据进行比较来量化。本研究的目的是提供参与澳大利亚东南部吉朗骨质疏松症研究的573名男性和923名女性(年龄在20 - 97岁)下肢肌肉力量和质量的标准数据。
在这项横断面研究中,使用尼古拉斯徒手肌力测试仪(一种手持式测力计,单位为千克)获取髋屈肌和髋外展肌的肌力测量值。通过双能X线吸收法(单位为千克)测量腿部瘦体重,并将肌肉质量计算为力量/质量(单位为牛/千克)。
对于男女两性,肌肉力量和质量均随年龄增长而下降。年龄解释了男性肌肉力量方差的12.9 - 25.3%,女性为20.8 - 24.6%;年龄对肌肉质量方差的解释较少。按年龄十年分组报告了各性别每个肌肉组的肌肉力量和质量的均值及标准差,并使用20 - 39岁年轻男性(n = 89)和女性(n = 148)的数据得出了相当于T值为 - 2.0和 - 1.0的切点。
这些数据将有助于量化普通人群中成年人在面对虚弱、肌肉减少症和其他与年龄相关的肌肉功能障碍时肌肉力量不足和肌肉质量差的程度。