Nikoleli Georgia-Paraskevi
Laboratory of Environmental & Sanitary Engineering, Department of Public Health, Faculty of Health and Caring Professions, University of West Attica, Athens, Greece.
Adv Food Nutr Res. 2020;91:301-321. doi: 10.1016/bs.afnr.2019.07.002. Epub 2019 Aug 1.
The investigation of lipid films for the construction of nanosensors has recently given the opportunity to manufacture devices to selectively determine a wide range of food toxicants. Biosensor miniaturization using recent advances in nanotechnology has given the opportunity to investigate novel techniques to immobilize a wide range of enzymes, antibodies and receptors within the lipid film. This chapter reviews novel revent platforms in nanobiosensors based on lipid membranes that are used in food chemistry to determine various food toxicants. Examples of applications are described with an emphasis on novel systems, sensing techniques and nanotechnology-based transduction schemes. The compounds that can be monitored are insecticides, pesticides, herbicides, metals, toxins, hormones, etc. Finally, limitations and future prospects are presented herein on the evaluation/validation and eventually commercialization of the proposed sensors.
最近,对用于构建纳米传感器的脂质膜的研究为制造能够选择性测定多种食品毒物的设备提供了契机。利用纳米技术的最新进展实现生物传感器的小型化,为研究在脂质膜内固定多种酶、抗体和受体的新技术提供了机会。本章综述了基于脂质膜的纳米生物传感器中的新型平台,这些平台用于食品化学中以测定各种食品毒物。文中描述了应用实例,重点介绍了新型系统、传感技术和基于纳米技术的转导方案。可监测的化合物包括杀虫剂、农药、除草剂、金属、毒素、激素等。最后,本文阐述了所提出的传感器在评估/验证以及最终商业化方面的局限性和未来前景。