Electrochemistry and Materials Group, Department of Chemistry, K. L. E. Institute of Technology, Affiliated to Visvesvaraya Technological University, Gokul, Hubballi, 580030, Karnataka, India.
Electrochemistry and Materials Group, Department of Chemistry, K. L. E. Institute of Technology, Affiliated to Visvesvaraya Technological University, Gokul, Hubballi, 580030, Karnataka, India.
Biosens Bioelectron. 2019 Sep 15;141:111417. doi: 10.1016/j.bios.2019.111417. Epub 2019 Jun 8.
Fascinating properties of ZnO nanostructures have created much interest due to their importance in health care and environmental monitoring. Current worldwide production and their wide range of applications signify ZnO to be a representative of multi-functional oxide material. Recent nanotechnological developments have stimulated the production of various forms of ZnO nanostructures such as nano-layers, nanoparticles, nanowires, etc. Due to their enhanced sensing properties, improved binding ability with biomolecules as well as biological activities have enabled them as suitable candidates for the fabrication of biosensor devices in the biomedical arena. In this review, the synthesis of ZnO nanostructures, mechanism of their interaction with biomolecules and their applications as sensors in health care area are discussed considering the biosensors for molecules with small molecular weight, infectious diseases, and pharmaceutical compounds.
氧化锌纳米结构的迷人性质因其在医疗保健和环境监测中的重要性而引起了广泛关注。目前全球的产量和广泛的应用表明，氧化锌是多功能氧化物材料的代表。最近的纳米技术发展刺激了各种形式的氧化锌纳米结构的生产，如纳米层、纳米粒子、纳米线等。由于其增强的传感性能、改善与生物分子的结合能力以及生物活性，使它们成为生物医学领域生物传感器器件制造的合适候选材料。在本综述中，考虑到用于小分子、传染病和药物化合物的传感器，讨论了氧化锌纳米结构的合成、与生物分子相互作用的机制及其在医疗保健领域作为传感器的应用。
