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用于快速检测食品中有毒物质的新型生物传感器。

Novel Biosensors for the Rapid Detection of Toxicants in Foods.

作者信息

Nikoleli Georgia-Paraskevi, Nikolelis Dimitrios P, Siontorou Christina G, Karapetis Stephanos, Varzakas Theo

机构信息

Laboratory of Inorganic & Analytical Chemistry, School of Chemical Engineering, Chemical Sciences, National Technical University of Athens, Athens, Greece.

Laboratory of Environmental Chemistry, University of Athens, Athens, Greece.

出版信息

Adv Food Nutr Res. 2018;84:57-102. doi: 10.1016/bs.afnr.2018.01.003. Epub 2018 Mar 7.

Abstract

The modern environmental and food analysis requires sensitive, accurate, and rapid methods. The growing field of biosensors represents an answer to this demand. Unfortunately, most biosensor systems have been tested only on distilled water or buffered solutions, although applications to real samples are increasingly appearing in recent years. In this context, biosensors for potential food applications continue to show advances in areas such as genetic modification of enzymes and microorganisms, improvement of recognition element immobilization, and sensor interfaces. This chapter investigates the progress in the development of biosensors for the rapid detection of food toxicants for online applications. Recent progress in nanotechnology has produced affordable, mass-produced devices, and to integrate these into components and systems (including portable ones) for mass market applications for food toxicants monitoring. Sensing includes chemical and microbiological food toxicants, such as toxins, insecticides, pesticides, herbicides, microorganisms, bacteria, viruses and other microorganisms, phenolic compounds, allergens, genetically modified foods, hormones, dioxins, etc. Therefore, the state of the art of recent advances and future targets in the development of biosensors for food monitoring is summarized as follows: biosensors for food analysis will be highly sensitive, selective, rapidly responding, real time, massively parallel, with no or minimum sample preparation, and platform suited to portable and handheld nanosensors for the rapid detection of food toxicants for online uses even by nonskilled personnel.

摘要

现代环境与食品分析需要灵敏、准确且快速的方法。生物传感器这一不断发展的领域满足了这一需求。遗憾的是,尽管近年来生物传感器在实际样品中的应用日益增多,但大多数生物传感器系统仅在蒸馏水或缓冲溶液中进行过测试。在此背景下,用于潜在食品应用的生物传感器在酶和微生物的基因改造、识别元件固定化的改进以及传感器界面等领域持续取得进展。本章探讨了用于在线快速检测食品毒物的生物传感器的发展进展。纳米技术的最新进展已制造出价格合理、可大规模生产的设备,并将其集成到用于食品毒物监测的面向大众市场应用的组件和系统(包括便携式系统)中。传感对象包括化学和微生物类食品毒物,如毒素、杀虫剂、农药、除草剂、微生物、细菌、病毒及其他微生物、酚类化合物、过敏原、转基因食品、激素、二恶英等。因此,食品监测生物传感器的最新进展及未来目标的技术现状总结如下:用于食品分析的生物传感器将具备高灵敏度、高选择性、快速响应、实时、大规模并行,无需或只需最少样品制备,且适合便携式和手持式纳米传感器平台,以便非专业人员也能在线快速检测食品毒物。

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