血铅与血压：对荷兰情况的一些启示

Blood lead and blood pressure: some implications for the situation in The Netherlands.

作者信息

de Kort W L, Zwennis W C

机构信息

Ministry of Social Affairs and Employment, Voorburg, The Netherlands.

出版信息

Environ Health Perspect. 1988 Jun;78:67-70. doi: 10.1289/ehp.887867.

DOI:10.1289/ehp.887867

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1474610/

Abstract

Studies performed earlier have shown a positive relation between blood lead (a parameter for lead body burden) and blood pressure, whereas such a relation between urine cadmium (a parameter for cadmium body burden) and blood pressure could not be shown. Median (i.e., 50th percentile, P50) blood levels in the general population in the Netherlands are in the range of 80 to 150 micrograms/L. Persons occupationally exposed to lead show median blood lead levels that may exceed 400 micrograms/L. To study causality, a prospective study among lead workers is desired.

摘要

早期进行的研究表明血铅（铅体内负荷的一个参数）与血压之间存在正相关关系，而尿镉（镉体内负荷的一个参数）与血压之间未显示出这种关系。荷兰普通人群的血铅中位数（即第50百分位数，P50）水平在80至150微克/升范围内。职业性接触铅的人的血铅中位数水平可能超过400微克/升。为了研究因果关系，需要对铅作业工人进行前瞻性研究。

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