Kechagias K, Anastasaki P, Kyriakidou M, Dedi K D
Department of Surgery and Cancer, Imperial College of London.
Eastman Dental Institute, UCL.
Eur J Prosthodont Restor Dent. 2020 Feb 27;28(1):3-9. doi: 10.1922/EJPRD_01950Kechagias07.
Bisphenol-A, an organic synthetic compound, has been present in many consumer plastic products and food packaging since the 1960s. Nowadays, Bisphenol-A is widely used in the field of dentistry for the manufacturing of resin materials. Several studies have suggested that Bisphenol-A may cause adverse health effects due to its ability to act as an endocrine disruptor chemical which has raised concerns about its widespread use. The aim of this study is to present an overview of the research studies dealing with Bisphenol-A exposure in the field of dentistry. PubMed, Scopus, EMBASE, Europe PMC, Web of Science and reference lists of relevant papers were searched to identify articles for inclusion. Two authors screened literature and extracted data from included studies independently. The evidence supports that Bisphenol A is used in many fields of routine clinical dental practice such as restorative dentistry and orthodontics. Regarding Bisphenol-A exposure from dental materials, the current data concludes that is below the Tolerable Daily Intake levels, but further evaluation is needed to reveal any possible adverse events caused by low-dose BPA exposure.
双酚A是一种有机合成化合物，自20世纪60年代以来，它一直存在于许多消费塑料制品和食品包装中。如今，双酚A在牙科领域被广泛用于制造树脂材料。几项研究表明，双酚A可能因其作为内分泌干扰化学物质的作用而对健康产生不良影响，这引发了人们对其广泛使用的担忧。本研究的目的是概述牙科领域中有关双酚A暴露的研究。通过检索PubMed、Scopus、EMBASE、欧洲PMC、科学网以及相关论文的参考文献列表来确定纳入的文章。两位作者独立筛选文献并从纳入的研究中提取数据。有证据表明，双酚A在常规临床牙科实践的许多领域都有应用，如修复牙科和正畸学。关于牙科材料中的双酚A暴露，目前的数据表明其低于每日可耐受摄入量水平，但需要进一步评估以揭示低剂量双酚A暴露可能导致的任何不良事件。
