Department of Obstetrics and Gynaecology, Epsom and St Helier University Hospitals NHS Trust, Epsom, UK.
2nd Department of Obstetrics and Gynaecology, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Neurourol Urodyn. 2020 Mar;39(3):880-889. doi: 10.1002/nau.24297. Epub 2020 Feb 10.
In the current climate of evidence-based health care, the aim of this meta-synthesis was to collect and systematically analyse data from primary qualitative studies on pelvic organ prolapse (POP), to identify patient-centered perspectives on the natural course of POP. Information acquired in this study may be useful for ongoing research towards the development of core outcome sets (COS) in pelvic floor disorders.
A CHORUS Working Group performed a standardized search of three different databases (Medline, Embase, Scopus), from inception to October 2019. We selected qualitative studies on women's perspectives on POP that were published in the English language. Three reviewers independently evaluated the quality of eligible papers and highlighted recurrent themes based on patient perspectives.
Eighteen qualitative studies including a total of 497 patients were assessed in this analysis. Our study revealed five superordinate themes, recurrently encountered in qualitative studies on POP: awareness of POP (6 studies), communication (9 studies), treatments (10 studies), effects on quality of life (6 studies), and self-image (3 studies). Five out of 10 quality criteria were met by all the studies included, based on an assessment performed using the critical appraisal skills program.
This is the first synthesis of qualitative studies that address POP-related experiences of women, highlighting five superordinate themes, of which treatment was the most commonly reported one. This synthesis' findings may guide quantitative research priorities and will hopefully contribute to the development of a COS for POP.
在当前循证医疗保健的背景下，本荟萃分析旨在收集和系统分析有关盆腔器官脱垂（POP）的主要定性研究数据，以确定患者对 POP 自然病程的看法。本研究获得的信息可能对正在进行的研究开发盆底疾病核心结局集（COS）有用。
一个 CHORUS 工作组对三个不同的数据库（Medline、Embase 和 Scopus）进行了标准化搜索，从开始到 2019 年 10 月。我们选择了关于女性对 POP 看法的定性研究，这些研究以英文发表。三位评审员独立评估合格论文的质量，并根据患者观点突出反复出现的主题。
在本分析中评估了 18 项包括总共 497 名患者的定性研究。我们的研究揭示了五个在 POP 定性研究中反复出现的超主题：POP 的意识（6 项研究）、沟通（9 项研究）、治疗（10 项研究）、对生活质量的影响（6 项研究）和自我形象（3 项研究）。根据使用批判性评估技能计划进行的评估，所有纳入的研究中有 5 项满足了 10 项质量标准中的 5 项。
这是首次对女性 POP 相关经历的定性研究进行综合分析，强调了五个超主题，其中治疗是最常报告的主题。本综合研究的结果可能指导定量研究的重点，并有望为 POP 的 COS 开发做出贡献。
