成功治疗一头患有口蹄疫的小牛的心律失常。
Successful treatment of cardiac dysrhythmia associated with foot and mouth disease in a calf.
作者信息
Priyanka M, Mahendran K, Umapathi V, Dechamma H J, Patel B H M, Reddy G R, Sanyal A
机构信息
Animal Experimentation Station, Indian Veterinary Research Institute, Regional Campus, Hebbal, Bengaluru-560024, India.
Division of Medicine, Indian Veterinary Research Institute, Bareilly-243122, Uttar Pradesh, India.
出版信息
Iran J Vet Res. 2019 Fall;20(4):304-307.
BACKGROUND
Foot and mouth disease (FMD), which causes myocarditis, results in 50% sudden death in the suckling calves. Occurrence of arrhythmias associated with FMD induced myocarditis in calves is not reported . The present work documents the arrhythmias associated with FMD in calf and their treatment using appropriate antiarrhythmic drugs.
CASE DESCRIPTION
A three -month-old male Holstein Friesian crossbred calf naturally suffering from FMD was selected for the present study.
FINDINGS/TREATMENT AND OUTCOME: Cardiac auscultation revealed grade 4 systolic murmurs and electrocardiography (ECG) showed sustained polymorphic ventricular premature complexes (PVPCs) with tachycardia on bipolar base apex lead. Apart from standard treatment, lidocaine 2% was administered at dose of 0.6 mg/kg intravenously over 15 min once a day and sinus rhythm was restored by 76 h post-treatment. Review of ECG and haematobiochemical examination revealed normal findings on 7th day of treatment.
CONCLUSION
The study demonstrates the presence of sustained PVPCs with tachycardia due to FMD induced myocarditis and the successful use of lidocaine in restoring the sinus rhythm and recovery of the calf.
背景
口蹄疫（FMD）可引发心肌炎，导致50%的哺乳犊牛突然死亡。目前尚无关于犊牛口蹄疫诱发心肌炎相关心律失常的报道。本研究记录了犊牛口蹄疫相关的心律失常情况以及使用适当抗心律失常药物对其进行的治疗。
病例描述
本研究选用了一头自然感染口蹄疫的3月龄雄性荷斯坦弗里生杂交犊牛。
研究结果/治疗与转归：心脏听诊显示有4级收缩期杂音，心电图（ECG）显示在双极基底部-心尖导联上存在伴有心动过速的持续性多形性室性早搏复合波（PVPCs）。除了标准治疗外，每天一次静脉注射2%利多卡因，剂量为0.6 mg/kg，持续15分钟，治疗后76小时恢复窦性心律。治疗第7天的心电图复查和血液生化检查结果均正常。
结论
该研究证明了口蹄疫诱发心肌炎会导致伴有心动过速的持续性PVPCs，且利多卡因在恢复窦性心律和犊牛康复方面使用成功。
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