Laboratoire d'Ecologie Microbienne, FSNV, Université de Bejaia, Bejaia, Algérie.
Expert Rev Anti Infect Ther. 2020 Mar;18(3):241-250. doi: 10.1080/14787210.2020.1729126. Epub 2020 Feb 19.
: The Middle East is actually recognized as endemic for carbapenemases-producing Enterobacterales (CPE) including at least OXA-48-like and NDM-like.: We performed a search of PubMed and Scopus using relevant keywords. We included peer-reviewed articles published only in English reporting any data on carbapenemase-producing bacteria from Middle East countries. The last literature search was performed on 26 October 2019. All studies describing carbapenemase-producing Enterobacterales isolated from humans, animals or environmental samples from the Middle East were included.: The Middle-East is considered an endemic region for CPE strains and the extensive international exchange could facilitate the spread of CPE from these countries to other parts of the Globe in which the prevalence of the CPE is low. The expansion of the Middle East conflict has been associated with the rapid collapse of the existing health care system of the concerned countries. Considering that Millions of refugees have fled their country, they could introduce these CPE strains in countries with low endemicity. In conclusion, the health care system actors should take in a count the endemicity of CPE in these countries and develop local surveillance programs to limit the spread of these MDR bacteria.
: 中东地区实际上被认为是碳青霉烯酶产生肠杆菌科（CPE）的地方性流行地区，包括至少 OXA-48 样和 NDM 样：我们使用相关关键词在 PubMed 和 Scopus 上进行了搜索。我们仅纳入了发表在英文期刊上、报告了来自中东国家产碳青霉烯酶细菌的任何数据的同行评议文章。最后一次文献检索是在 2019 年 10 月 26 日进行的。所有描述从中东地区人类、动物或环境样本中分离出的产碳青霉烯酶肠杆菌科的研究都被包括在内。：中东地区被认为是 CPE 菌株的地方性流行地区，广泛的国际交流可能会促进这些国家的 CPE 菌株传播到全球其他流行率较低的地区。中东冲突的扩大与有关国家现有卫生保健系统的迅速崩溃有关。考虑到数以百万计的难民逃离了他们的国家，他们可能会将这些 CPE 菌株引入流行率较低的国家。总之，卫生保健系统的参与者应该考虑到这些国家 CPE 的地方性流行情况，并制定本地监测计划，以限制这些耐多药细菌的传播。
